Nucleotide analogs

Details Nucleotide analogs Nucleotide analogs

2004-06-29

2008-10-21

Lukton, David (Department: 1654)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C536S022100, C536S025340, C536S027140, C536S027210, C562S553000

Reexamination Certificate

active

07439350

ABSTRACT:
Nucleotide analogs characterized by the presence of an amidate linked amino acid or an ester linked group which is bonded to the phosphorus atom of phosphonate nucleotide analogs are disclosed. The analogs comprise a phosphoamidate or ester bond that is hydrolyzed in vivo to yield a corresponding phosphonate nucleotide analog. Methods and intermediates for their synthesis and use are described.

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