Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing nitrogen-containing organic compound
Reexamination Certificate
2004-06-03
2008-03-18
Puttlitz, Karl (Department: 1621)
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing nitrogen-containing organic compound
C435S135000
Reexamination Certificate
active
07344868
ABSTRACT:
The invention relates to the fields of fatty substance chemistry, specifically of the ceramide-type compound synthesis. The invention resides substantially in the synthesis of ceramide-type compounds. Specifically, the aim of the invention is a new enzymatic synthesis method, comprising at least one amidification step and one esterification step, achieved through lipases, among fatty acids and/or esters thereof and amino alcohols. The resulting ceramide-type compounds can be used as cosmetic and/or pharmaceutical compositions, in particular as dermatological compositions in conjunction or in admixture with one or more suitable cosmetic and/or pharmaceutical excipients or carriers. The method has an interest particularly in the synthesis of active compounds useful in the fields of cosmetology and/or pharmacology and specifically of dermatology.
REFERENCES:
patent: 2276902 (2000-01-01), None
Maugard et al., Enzymatic synthesis of glycamide surfactants by amidification reaction, Tetrahedron, vol. 53, Issue 14, Apr. 7, 1997, pp. 5185-5194.
Bartling et al., Lipase-catalyzed synthesis of geranyl acetate in n-hexane with membrane-mediated water removal, Biotechnology and Bioengineering vol. 75, Issue 6, Date: Dec. 20, 2001, pp. 676-681.
Lassalle Laurent
Yvergnaux Florent
Muserlian Charles A.
Puttlitz Karl
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