Optically active 1-5-disubstituted-2,4-o-isopropylidene-2,4-dihy

Details Optically active 1-5-disubstituted-2,4-o-isopropylidene-2,4-dihy Optically active 1-5-disubstituted-2,4-o-isopropylidene-2,4-dihy

1993-06-04

1994-07-12

Richter, Johann

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

549375, C07D31906

Patent

active

053290186

ABSTRACT:
A novel optically active erythro-1-alkanoyloxy-2,4-O-isopropylidene-2,4-dihydroxy-5-substituted pentane expressed by the formula ##STR1## wherein R.sup.1 represents a halogen atom or cyano group and R.sup.2 represents an alkyl group of 1 to 6 carbon atoms, and a process for producing the above compound are provided, the compound being preferably usable as an intermediate for preparing a HMG-CoA reductase inhibitor and the process being practiced under mild conditions and with a high yield.

REFERENCES:
Horvath et al. Chem. Abst. vol. 91, No. 11; 91886m (1979).
Zarubinskii et al. Chem. Abst. vol. 70, No. 13; 58187c (1969).
Kuszmann et al. Chem. Abst. vol. 75, No. 5; 36533p (1971).

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