Treatment of inflammatory, cancer, and thrombosis disorders

Details Treatment of inflammatory, cancer, and thrombosis disorders Treatment of inflammatory, cancer, and thrombosis disorders

2001-08-30

2008-03-04

Kwon, Brian (Department: 1614)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C514S432000, C514S413000, C514S455000, C514S161000

Reexamination Certificate

active

07338971

ABSTRACT:
This invention provides for the treatment of inflammatory, cancer and thrombotic disorders through the administration, in combination, of a COX2 inhibitor, low dose aspirin, and antioxidant flavanoids, flavonoids or isoflavones and at least one of these combinations will be given in a subtherapeutic amount for improved anti-inflammatory, anti-cancer, and anti-thrombotic efficacy and safety.

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“Anti-inflammatory and anti-allergic properties of flavonoids”, Gabor M., Prog Clin Biol Res 213:471-480, 1986.
“A New Cyclooxygenase-2 Inhibitor, Rofecoxib (VIOXX), Did Not Alter the Antiplatelet Effects of Low-Dose Aspirin in Healthy Volunteers”, Greenberg et al., Journal of Clinical Pharmacology, 2000, 40(12. Pt2), pp. 1509-1515.
Drug Facts and Comparison, 1995 Edition, pp. 1248.

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