Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1992-10-21
1994-07-12
Fan, Jane T.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
546273, 546270, 546256, 514338, 514333, C07D40112, A61K 3144
Patent
active
053289200
ABSTRACT:
There are disclosed various compounds of the formula below, ##STR1## where R, R.sub.1, W, X, Y and Z are as defined in the specification; which are useful for alleviating various memory dysfunctions such as Alzheimer's disease, as modulators of neurotransmitter functions such as serotonergic and adrenergic, and as such are useful as antidepressants, anxiolytics, atypical antipsychotics, antiemetics, and for the treatment of personality disorders such as obsessive compulsive disorder.
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Houlihan, ed. "Indoles", Part II, 210-212 Wiley-Interscience (1972).
Effland Richard C.
Kapples Kevin J.
Klein Joseph T.
Martin Lawrence L.
Shutske Gregory M.
Fan Jane T.
Hoechst-Roussel Pharmaceuticals Incorporated
Ikeda Tatsuya
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