Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Reexamination Certificate
2004-05-10
2008-03-04
Kam, Chih-Min (Department: 1656)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
C514S017400, C424S009100, C530S328000, C530S329000, C530S316000, C435S375000
Reexamination Certificate
active
07338938
ABSTRACT:
The present invention provides improved methods, kits, and pharmaceutical compositions for increasing hematopoietic cell survival and/or reducing or preventing the side effects of chemotherapy, and mobilizing hematopoietic progenitor cells from bone marrow into peripheral blood following chemotherapy, comprising administering an effective amount angiotensinogen, angiotensin I (AI), AI analogues, AI fragments and analogues thereof, angiotensin II (AII) AII analogues, AII fragments or analogues thereof or AII AT2type 2 receptor agonists to a patient in need of chemotherapy.
REFERENCES:
patent: 5015629 (1991-05-01), diZerega et al.
patent: 5595973 (1997-01-01), Bodgen et al.
patent: 5605931 (1997-02-01), Hanson et al.
patent: 5629292 (1997-05-01), Rodgers et al.
patent: 5693616 (1997-12-01), Krstenansky et al.
patent: 5716935 (1998-02-01), Rodgers et al.
patent: 5834432 (1998-11-01), Rodgers et al.
patent: 5955430 (1999-09-01), Rodgers et al.
patent: 6475988 (2002-11-01), Rodgers et al.
patent: 6566335 (2003-05-01), Rodgers et al.
patent: 6762167 (2004-07-01), Rodgers et al.
patent: 7176183 (2007-02-01), Rodgers et al.
patent: WO 95/08337 (1995-03-01), None
patent: WO 95/08565 (1995-03-01), None
patent: WO 96/14858 (1996-05-01), None
patent: WO 96/15795 (1996-05-01), None
patent: WO 96/39164 (1996-12-01), None
patent: WO 96/40090 (1996-12-01), None
patent: WO 97/27867 (1997-08-01), None
patent: WO 97/34627 (1997-09-01), None
patent: WO 98/26795 (1998-06-01), None
patent: WO 98/32457 (1998-07-01), None
patent: WO 98/33813 (1998-08-01), None
Leonard Bell and Joseph A. Madri, “Influence of the Angiotensin System on Endothelial and Smooth Muscle Cell Migration,” American journal of Pathology, vol. 137, No. 1 (1990) pp. 7-12.
Bradford C. Berk, Vladimir Vekshtein, helen M. Gordon, Terutaka Tsuda, “Angiotensin II-Stimulated Protein Synthesis in Cultured Vascular Smooth Muscle Cells,” Hypertension vol. 13 (1989) pp. 305-314.
Susan E. Bryson, Philip Warburton, helen P. wintersgill, G. Michael Drew, Anton D, Michel, Stephen G. Ball and Anthony J. Balmforth, “Induction of the Angiotensin AT2Receptor Subtype Expression by Differentiation of the Neuroblastoma x Glioma Hybrid, NG-108-15,” European Journal of Pharmacology, vol. 225 (1992) pp. 119-127.
Felipe G. Elizondo, Jr. and Cynthia Sung, :Effect of Angiotensin II on Immunotoxin Uptake in Tumor and Normal Tissue, Cancer Chemotherapy Pharmacology, vol. 39 (1996) pp. 113-121.
Rose-Marie Catalioto, Anna-Rita Renzetti, Marco Criscuoli, Jacques Mizrahi and Allessandro Subissi, “Angiotensin Induce the Release of Prostacyclin from Rabbit Vas Deferens: Evidence for Receptor Heterogeneity,” European Journal of Pharmacology, vol. 256 (1994) pp. 94-97.
W.M. Clouston, B.A. Evans, J. Haralambids and R.I. Richards, “Molecular Cloning of the Mouse Angiotensinogen Gene,” Genomics, vol. 2 (1988) pp. 240-248.
M.J. Dworkin, P. Carnochan and T.G. Allen-Mersh, “Effect of Continuous Regional Vasoactive Agent Infusion on Liver Metastasis Blood Flow,” British Journal of Cancer, vol. 76, No. 9 (1997) pp. 1205-1210.
Victor E. Dzau, Richard pratt, Gary Gibbons, heribert Schunkert, Beverly Lorell and Julie Ingelfinger, “Molecular Mechanism of Angiotensin in the Regulation of Vascular and Cardiac Growth,” Journal of Molecular Cell Cardiology, vol. 21 (Supplement III) (1989) p. S.7.
Richard M. Edwards and Elwood J. Stack, “Angiotensin II Inhibits Glomerular Adenylate Cyclase via the Angiotensin II Receptor Subtype 1 (AT1),” The Journal of Pharmacology and Experimental Therapeutics, vol. 266, No. 2 (1993) pp. 506-510.
Leonardo A. Fernandez, jeff Twickler and Alden Mead, “Neovascularization Produced by Angiotensin II,” vol. 105, No. 2 (1985) pp. 141-145.
Neelam Jaiswal, Debra I. Diz, Mark C. Chappell, Mahesh C. Khosla and Carlos M. Ferrario, “Stimulation of Endothelial Cell Prostaglandin Production by Angiotensin Peptides,” Hypertension, vol. 19 (Supplement II) (1992) pp. II-49-II-55.
Neelam Jaiswal, E. Ann Tallant, Rama K. Jaiswal, Debra I. Diz and Carlos M. Ferrario, “Differential Regulation of Prostaglandin Synthesis b Angiotensin Peptides in Porcine Aortic Smooth Muscle Cells: Subtypes of Angiotensin Receptors Involved,” The Journal of Pharmacology and Experimental Therapeutics, vol. 265, No. 2 (1993) pp. 664-673.
Neelam Jaiswal, E. Ann Tallant, Debra I. Diz, mahesh C. Khosla and Carlos M. Ferrario, “Subtype 2 Angiotensin Receptors Mediate Prostaglandin Synthesis in Human Astrocytes,” Hypertension, vol. 17 (1991) pp. 1115-1120.
Philip Janiak, Aline Pillon, Jean-Francois and Jen-Paul Vilaine, “Role of Angiotensin Subtype 2 Receptor in Neointima Formation After Vascular Injury,” Hypertension, vol. 20 (1992) pp. 737-745.
Joaquin J. Jimenez and Adel A. Yunis, “Protection from 1-β-D-Arabinofuranosylcytosine-Induced Alopecia by Epidermal Growth factor and Fibroblast Growth Factor in the Rat Model,” cancer Research, vol. 52 (1992) pp. 413-415.
Ryoichiro Kageyama, Hiroaki Ohkubo and Shigetada Nakanishi, “Primary Structure of Human Preangiotensinogen Deduced from the Cloned cDNA Sequence,” Biochemistry, vol. 23 (1984) pp. 3603-3609.
Kauffman et al., (1991), Life Sci., “Losartan, a nonpeptide angiotensin II (ANGII) receptor antagonist, inhibits neointima formation following balloon injury to rat carotid arteries”, vol. 49, pp. 223-228.
Yasuhiro Kawahara, Michitoshi Suanko, Terutaka Tsuda, Hisashi Fukuzaki, Yasuo Fukumoto and Yoshimi Takai, “Angiotensin II induces Expression of the C-FOS gene Through Protein Kinase C Activation and Cacium Ion Mobilization in Cultured Vascular Smooth Muscle Cells,” Biochemical and Biophysical Research Communications, vol. 150, No. 1 (1988) pp. 52-59.
Birgitta Kimura, Colin Sumners and M. Ian Phillips, “Changes in Skin Angiotensin II Receptors in Rats During Wound Healing,” Biochemical and Biophysical Research Communication, vol. 187, No. 2 (1992) pp. 1083-1090.
Toshiro Kuroiwa, Seiji Naito, Nanehiro Hasuo, Takashi Kishikawa, Kouji Masuda and Jyoichi Kumazawa, “Phase II Study of a New Combined Primary Chemotherapy Regimen, Intravenous Methotrexate and Vincristine and Intraarterial Adriamycin and Cisplatin, for locally Advanced Urinary Blader Cancer: Preliminary Results,” Cancer Chemotherapy Pharmacology, vol. 35 (1995) pp. 357-363.
Ferdinand A.C. Le Noble, Johan W.M. Hekking, Henny W.M. Van Straaten, Dick W. Slaaf and Harry A.J. Struyker Boudier, “Angiotensin II Stimulates Angiotensin in the Chorio-Allantoic Membrane of the Chick Embryo,” European Journal of Pharmacology, vol. 195 (1991) pp. 305-306.
C.J. Li, Y. Miyamoto, Y. Kojima and H. Maeda, “Augmentation of Tumor Delivery of Macromolecular Drugs with Reduced Bone Marrow Delivery by Elevating Blood Pressure,” Br. J. Cancer, vol. 67 (1993) pp. 975-980.
Tatsuo Morita, Takao Kikuchi, Yosuke Hara, Shinya Ishikawa, Yutaka Koboyashi, Shunji Ishiyama, Kazuhiko Tozuka, Kentaro Goto, Kouji Takahashi, Hiroyuki Yoshikawa, Osamu Tanaka and Akihiko Tokue, “Intrarterial Infusion Chemotherapy with [Sar1, I1e8] Angiotensin II for Bladder Cancer,” American journal of Clinical Oncology, vol. 15, No. 3 (1992) pp. 188-193.
Mrug, M., et al., (1997), J. Clin. Invest., vol. 100, pp. 2310-2314.
Shinji Mutoh, iwao Aikou, Kazuaki Soejima, Shoichi ueda, Shoji Fukushima, Shuichi Kishimoto and Yoshikazu Takagi, “Local Control of Prostate Cancer by Intraarteruak Infusion Chemotherapy Facilitated by the use of Angiotensin II,” Urol. Int., vol. 48 (1992) pp. 175-180.
Allen J. Nauftilan, Richard E. Pratt and Victor Dzau, “Induction of Platelet-Derived Growth Factor A-Chain and c-myc Gene Expressions by Angiotensin II in Cultured Rat Vascular Smooth Muscle Cells,” Journal of Clinical Investigations, vol. 83 (1989) pp. 1419-1423.
Ken-ichi Nakahara, Hiroshi Nishimura, Makoto Kuro-o, Shun-ichi
diZerega Gere
Rodgers Kathleen
Kam Chih-Min
McDonnell Boehnen & Hulbert & Berghoff LLP
University of Southern California
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