Optical waveguides – Optical waveguide sensor
Reexamination Certificate
2005-09-26
2008-03-25
Kim, Ellen E. (Department: 2874)
Optical waveguides
Optical waveguide sensor
C385S037000
Reexamination Certificate
active
07349590
ABSTRACT:
An optical interrogation system and a GCW sensor are described herein that are used to determine whether a biological substance (e.g., cell, molecule, protein, drug) is located in a sensing region of the GCW sensor. The optical interrogation system includes a light source, a polarization modulator and a detection system. The light source outputs a polarized light beam and the polarization modulator modulates the polarized light beam and outputs a polarization-modulated light beam. The GCW sensor receives and converts the polarization-modulated light beam into an amplitude modulated light beam that is directed towards the detection system. The detection system receives the amplitude modulated light beam and demodulates the received amplitude modulated light beam by responding to signals at a modulation frequency of the polarization-modulated light beam and ignoring noise affecting the signals outside the modulation frequency to detect a resonant condition (e.g., resonant angle, resonant wavelength). The detected resonant condition that has a one-to-one relationship with the refractive index of the superstrate containing the biological substance is analyzed to determine whether or not the biological substance is located in the sensing region of the GCW sensor.
REFERENCES:
patent: 4552578 (1985-11-01), Anderson
patent: 5008558 (1991-04-01), Koshinaka et al.
patent: 5094517 (1992-03-01), Franke
patent: 5104222 (1992-04-01), Kersey et al.
patent: 5479260 (1995-12-01), Fattinger
patent: 5738825 (1998-04-01), Rudigier et al.
patent: 5886810 (1999-03-01), Siahpoushan et al.
patent: 6002480 (1999-12-01), Izatt et al.
patent: 6312961 (2001-11-01), Voirin et al.
patent: 6421164 (2002-07-01), Tearney et al.
patent: 6455004 (2002-09-01), Tiefenthaler
patent: 6483096 (2002-11-01), Kunz et al.
patent: 6707561 (2004-03-01), Budach et al.
patent: 6903815 (2005-06-01), Uchiyama et al.
patent: 7186567 (2007-03-01), Sutherland et al.
patent: 2002/0127565 (2002-09-01), Cunningham et al.
patent: 2002/0130262 (2002-09-01), Nakasuji et al.
patent: 2002/0131476 (2002-09-01), Baba et al.
patent: 2002/0168295 (2002-11-01), Cunningham et al.
patent: 2003/0017580 (2003-01-01), Cunningham et al.
patent: 2003/0017581 (2003-01-01), Li et al.
patent: 2003/0026891 (2003-02-01), Qiu et al.
patent: 2003/0027327 (2003-02-01), Cunningham et al.
patent: 2003/0027328 (2003-02-01), Cunningham et al.
patent: 2003/0032039 (2003-02-01), Cunningham et al.
patent: 2003/0059855 (2003-03-01), Cunningham et al.
patent: 2003/0068657 (2003-04-01), Lin et al.
patent: 2003/0077660 (2003-04-01), Pien et al.
patent: 2003/0092075 (2003-05-01), Pepper
patent: 2003/0113766 (2003-06-01), Pepper et al.
patent: 2004/0132172 (2004-07-01), Cunningham et al.
patent: 2004/0132214 (2004-07-01), Lin et al.
patent: 2004/0151626 (2004-08-01), Cunningham et al.
patent: 2004/0223881 (2004-11-01), Cunningham et al.
patent: 2005/0078924 (2005-04-01), Viellerobe et al.
N.H. Fontaine et al., “Variable-angle internal-reflection Raman spectroscopy for depth-resolved vibrational characterization of polymer thin films”, Physical Review B, vol. 57, No. 7, Feb. 15, 1998—1, pp. 3807-3810.
A. Brandenburg et al., “Grating couplers as chemical sensors: a new optical configuration”, Sensors and Accuators R, pp. 35-40.
Beall Thomas R.
Corning Incorporated
Kim Ellen E.
Tucker William J.
LandOfFree
Polarization modulation interrogation of grating-coupled... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Polarization modulation interrogation of grating-coupled..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Polarization modulation interrogation of grating-coupled... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3963286