Chemistry: molecular biology and microbiology – Process of mutation – cell fusion – or genetic modification
Reexamination Certificate
2008-04-15
2008-04-15
Qian, Celine (Department: 1636)
Chemistry: molecular biology and microbiology
Process of mutation, cell fusion, or genetic modification
C435S455000, C536S023100
Reexamination Certificate
active
10239595
ABSTRACT:
The invention relates to improved methods for the modification, including recombination, of genes in cells. More specifically, the invention relates to the increased efficiency of modification, including recombination, by introduction of a DNA-modifying molecule into a cell cycle synchronized cell. Additionally, the invention relates to target DNA that has been modified, mutated or marked by the approaches disclosed herein. The invention also relates to cells, tissue, and organisms which have been modified by the invention's methods.
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Majumdar Alokes
Seidman Michael M.
Klarquist & Sparkman, LLP
Qian Celine
The United States of America as represented by the Department of
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