Polysubstituted 1,1-pyridyloxycyclopropanamine compounds

Details Polysubstituted 1,1-pyridyloxycyclopropanamine compounds Polysubstituted 1,1-pyridyloxycyclopropanamine compounds

2008-03-25

2008-03-25

Davis, Zinna N. (Department: 1625)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C546S290000

Reexamination Certificate

active

11493070

ABSTRACT:
A compound selected from those of formula (I):wherein:n represents an integer from 1 to 6 inclusive,R1and R2represent a hydrogen atom, a (C1-C6)alkyl group or an aryl-(C1-C6)alkyl group,R3and R4represent a hydrogen atom or a (C1-C6)alkyl group,R5and R6represent a hydrogen atom, or a (C1-C6)alkyl, halogen, hydroxy, (C1-C6)alkoxy, cyano, nitro, (C2-C6)acyl, (C1-C6)alkoxycarbonyl, (C1-C6)trihaloalkyl, (C1-C6)trihaloalkoxy or optionally substituted amino group,its enantiomers, diastereoisomers and additional salts thereof with a pharmaceutically acceptable acid or base.Medicinal products containing the same which are useful in the treatment of conditions requiring a specific nicotinic ligand of α4β2 receptors.

REFERENCES:
patent: 1170281 (2002-01-01), None
French Preliminary Search Report for FR05.08033 of Jun. 12, 2006.

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