Multiplexed electrochemical detection system and method

Details Multiplexed electrochemical detection system and method Multiplexed electrochemical detection system and method

2008-03-11

2008-03-11

Forman, BJ (Department: 1634)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

C435S283100, C435S288400, C422S068100, C422S082010

Reexamination Certificate

active

11011490

ABSTRACT:
Multiplexed analysis of molecular structures of samples. A plurality of sample wells is arranged on a substrate. A plurality of electrodes is fabricated on a first side of the substrate. The electrodes are disposed on the side of the substrate exposed to the sample wells. The electrodes include working electrodes, counter electrodes, and optionally include reference electrodes. At least two of the sample wells includes a plurality of working electrodes. The plurality of electrodes is configured to allow electrochemical analysis of the associated sample wells in a multiplexed fashion. The plurality of electrodes is electrically coupled to an interface to a sample analysis system. The interface to the sample analysis system can include contacts or connections. The sample analysis system controls a signal to the electrodes in a multiplexed fashion and performs the electrochemical analysis.

REFERENCES:
patent: 5545531 (1996-08-01), Rava et al.
patent: 6331441 (2001-12-01), Balch et al.
patent: 6468742 (2002-10-01), Nerenberg et al.
patent: 6673533 (2004-01-01), Wohlstadter et al.
patent: 2002/0090649 (2002-07-01), Chan et al.
patent: 2002/0123048 (2002-09-01), Gau, Jr.
patent: 2004/0022677 (2004-02-01), Wohlstadter et al.
patent: 2004/0086892 (2004-05-01), Crothers et al.
patent: 2004/0086894 (2004-05-01), Crothers et al.
patent: WO 01/83674 (2001-11-01), None
Steel et al.,Electrochemical Quantitation Of DNA Immobilized On Gold, Analytical Chemistry, vol. 70, No. 22, pp. 4670-4677, Nov. 15, 1998.
Popovich et al.,New Strategies for Electrochemical Nucleic Acid Detection, The Electrochemical Society Interface, Winter, 2002.
Vernon et al.,Bioelectric DNA Detection of Human Papillomaviruses Using eSensor™: A Model System for Detection of Multiple Pathogens, BMC Infectious Diseases 2003, 3:12 available at http://www.biomedcentral.com/1471-2334/3/12.
Popovich,Mediated Electrochemical Detection of Nucleic Acids for Drug Discovery and Clinical Diagnostics, Originally published IVD Technology Apr. 2001, http://www.devicelink.com/grabber.php3?URL=http://www.devicelink.com/ivdt/archive/01/04/001/html (Oct. 20, 2003).
Brochure: Gamry Instruments,PHE200 Physical Electrochemistry Softwarehttp://www.gamry.com/Products/PHE200.htm (Oct. 17, 2003).
Chronoamperometry/Chronocoulometry, http://www.epsilon-web.net/Ec/manual/Techniques/ChronoI/ca.html (Oct. 17, 2003).
CHM 320—April Lectures Chapter 14, pp. 33-50 http://www.nau.edu/chem/faculty/ingram/images/CHM—320—April—Lectures.pdf.

Affiliated with

Also associated with

Rating

Multiplexed electrochemical detection system and method does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Multiplexed electrochemical detection system and method, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Multiplexed electrochemical detection system and method will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3955376