Drug – bio-affecting and body treating compositions – Enzyme or coenzyme containing – Hydrolases
Reexamination Certificate
2008-09-16
2008-09-16
Weber, Jon P (Department: 1652)
Drug, bio-affecting and body treating compositions
Enzyme or coenzyme containing
Hydrolases
C435S219000, C606S007000
Reexamination Certificate
active
11534351
ABSTRACT:
The use of a collagenase containing formulation for degrading collagen within an occlusive atherosclerotic plaque in a chronic fibrotic occlusion, chronically occluded animal tube or cavity. A medical-related apparatus is provided comprising a medical-related device having provided thereto a therapeutic amount of a collagen degrading composition comprising a proteiolytic enzyme containing formulation. A method is provided for treating chronically occluded animal tubes and cavities by administering a therapeutic effective amount of a proteolytic enzyme-containing formulation adjacent to an occluding atherosclerotic plaque, waiting for a pre-angioplasty waiting period, followed by crossing the plaque with an angioplasty guide wire.
REFERENCES:
patent: 4636195 (1987-01-01), Wolinsky
patent: 5024829 (1991-06-01), Berger et al.
patent: 5163421 (1992-11-01), Bernstein et al.
patent: 5328470 (1994-07-01), Nabel et al.
patent: 5422261 (1995-06-01), Lee et al.
patent: 5503850 (1996-04-01), O'Rear, III et al.
patent: 5813949 (1997-03-01), Miraki
patent: 5955584 (1999-09-01), Ditlow et al.
patent: 6306166 (2001-10-01), Barry et al.
patent: 2002/0077594 (2002-06-01), Chien et al.
patent: 2002/0082221 (2002-06-01), Herrmann et al.
patent: 0 920 882 (1999-06-01), None
patent: 1060747 (2000-12-01), None
patent: 03/028639 (2003-04-01), None
Yoon, H.C. et al., “A Porcine Model of Chronic Peripheral Arterial Occlusion,” Journal of Vascular and Interventional Radiology: JVIR. United States, 1996, Jan.-Feb., vol. 7, No. 1, Jan. 1996, pp. 65-74 (XP009003811) (ISSN: 1051-0443) “Surgical and Angiographic Protocol” (10 pages).
Kerenyi et al., “Local enzymatic treatment of atherosclerotic plaques,” Exp Mol Path 49:330-338, 1988 (9 pages).
Sigma-Aldrich catalog excerpt for collagenase Type 1A from Colstridium histolyticum, http://www.sigmaaldrich.com/catalog/search/Search Results Page/Expand, printed on Jan. 12, 2006 (3 pages).
International Union of Biochemistry and Molecular Biology, Enzyme Nomenclature on line, EC 3.4.24.3, record for collagenase, http://www.chem.qmul.ac.uk/iubmb/enzyme/EC3/4/24/3.html, printed on Jan. 12, 2006 (2 pages).
Sionis et al., “Chronic Total Coronary Occlusions: A Review of their Special Features and the Existing Techniques of Percutaneous Treatment,” Hellenic Journal of Cardiology, 44:136-142, 2003 (7 pages).
Puma et al., “Percutaneous revascularization of chronic coronary occlusions: an overview,” J Am Coll Cardiol 26(1):1-11, 1995 (11 pages).
Enzyme Nomenclature (Web Version of Enzyme Nomenclature Committee of the International Union of Biochemistry and Molecular Biology (NC-IUBMB), record for t-PA and urokinase at http://www.chem.qmul.ac.uk/iubm/enzyme/EC3/4/21/88.html, printed on May 15, 2006 (2 pages).
Enzyme Nomenclature (Web Version of Enzyme Nomenclature Committee of the International Union of Biochemistry and Molecular Biology (NC-IUBMB), record for urokinase at http://www.chem.qmul.ac.uk/iubm/enzyme/EC3/4/21/73.html, respectively, printed on May 15, 2006 (1 pages).
International Search Report from PCT Application No. PCT/CA2005/000539 filed Apr. 8, 2005 (3 pages).
Stone, Gregg W., et al, Parcutaneous Recanalization of Chronically Occluded Arteries. A Consensus Document, Circulation, Oct. 11, 2005, 2364-72, vol. 112, 2005 American Heart Association, Inc. (9 pages).
Strauss, Bradley H., et al, Collagenase Plaque Digestion for Facilitating Guide Wire Crossing in Chronic Total Occlusions, Circulation, Sep. 9, 2003, 1259-1262, vol. 108(10), 2003 American Heart Association, Inc. (4 pages).
Zidar, Frank J. et al, Prospective, Randomized Trial of Prolonged Intracoronary Urokinase Infusion for Chronic Total Occlusions in Native Coronary Arteries, JACC, May 1998, 1408-12, vol. 27, No. 8, American College of Cardiology (7 pages).
Hartmann, Joseph R., et al, Recanalization of Chronically Occluded Aortocoronary Saphenous Vein Bypass Grafts by Extended Infusion of Urokinase, Initial Results And Short-Term Clinical Follow-Up, JACC, Nov. 15, 1991, 1517-23, vol. 18, No. 9, American College of cardiology (7 pages).
Ruocco, Jr., Nicholas A., et al, Experience with Low-Dose Intracoronary Recombinant Tissue-Type Plasminogen Activator for Nonacute Total Occlusions Before Percutaneous Transluminal Coronary Angioplasty, The American Journal of Cardiology, Dec. 15, 1991, 1609-13, vol. 68 (5 pages).
Hartmann, Joseph, et al, Prolonged Infusion of Urokinase for Recanalization of Chronically Occluded Aortocoronary Bypass Grafts, The American Journal of Cardiology, Jan. 1, 1988, 189-191, vol. 61 (3 pages).
Braunwald, Eugene, et al, (Editors), Braunwald's Heart Disease, A Textbook of Cardiovascular Disease, 5th Edition, 1997, Chapter 58, pp. 1814-1815, W.B. Saunders Co. (2 pages).
Topol, Eric J., et al., (Editors), Textbook of Interventional Cardiology, 3rd Edition, 1999, Chapter 5, pp. 78-79, W.B. Saunders Co. (2 pages).
European Search Report and Annex thereto, established on European Patent Office Application No. 2,764,443, (3 pages) Apr. 24, 2007.
Claims 1-22 on which Search Report on European Patent Office Application No. 2,764,443 of Apr. 24, 2007 was established.
Kumar, Vinay et al., Tissue Renewal and Repair; Regeneration, Healing, and Fibrosis, Chapter 3, In: Robbins & Coltran Pathologic Basis of DIsease, Seventh Edition, Philadelphia 2005: pp. 107, 110, 111, 115 and 116.
Song, Woohyuk et al., Rapid Communication: A New Percutaneous Porcine Coronary Model of Chronic Total Occlusion, The Jounal of Invasive Cardiology. Sep. 9, 2005 17(9): pp. 452-454.
Yoon, Hyo-Chun, et al., A Porcine Model of Chronic Peripheral Arterial Occlusion, Journal of Vascular and Interventional Radiology, Jan. 1996; 7: pp. 65-74.
Kosson Rosanne
Torys LLP
Weber Jon P
LandOfFree
Use of collagenase to facilitate guide wire crossing in... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Use of collagenase to facilitate guide wire crossing in..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Use of collagenase to facilitate guide wire crossing in... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3954333