Urease antigen product and process

Details Urease antigen product and process Urease antigen product and process

1987-03-12

1989-06-06

Foelak, Morton

Drug, bio-affecting and body treating compositions

Lymphokine

424 92, 530403, A61K 3900

Patent

active

048370177

ABSTRACT:
The present invention relates to a non-enzymatic and non-toxic urease antigen and a method for its production. Administration of the urease antigen in living organisms serves to immunize the same from certain types of ammonia production without causing ammonia toxicity when injected, thereby promoting several advantageous biological activities including the promotion of wound healing, and general immunity from ammonia toxicity and the related effects thereof, and the cessation of toxic ammonia production in infections caused by urea splitting organisms.

REFERENCES:
patent: 3876504 (1975-04-01), Koffler
patent: 4004979 (1977-01-01), Avrameas et al.
patent: 4246351 (1981-01-01), Miyake et al.
patent: 4464468 (1984-08-01), Avrameas et al.
Hedelin et al., "Urease-Induced Crystallization In Synthetic Urine", J. of Urol., vol. 133, 529-532.
Stalheim et al., "Ureaplasmal Epithelial Lesions Related to Ammonia", Infec. & Imm., 3/1977; 15(3); 995-6.

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