Chemistry: molecular biology and microbiology – Apparatus – Including measuring or testing
Reexamination Certificate
2008-09-02
2008-09-02
Corcoran, Gladys (Department: 1797)
Chemistry: molecular biology and microbiology
Apparatus
Including measuring or testing
C435S288400, C435S288300, C435S287800, C435S305300, C435S305100, C435S278000
Reexamination Certificate
active
10688904
ABSTRACT:
A device for monitoring leukocyte migration is provided. The invention also provides a method of using the device to monitor leukocyte migration in the presence of physiological shear flow and therefore simulate physiological conditions of a blood vessel in vivo. The invention further provides a method of using the device to high-throughput screen a plurality of test agents. The present invention further provides a flexible assay system and numerous assays that can be used to test biological interactions and systems. Laminar flow gradients are employed that mimic gradient situations present in vivo.
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Kim Enoch
Kirk Gregory L.
Ostuni Emanuele
Schueller Olivier
Sweetnam Paul
Bowers Nathan A.
Corcoran Gladys
Kenyon & Kenyon LLP
Surface Logix Inc.
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