Arylhydroxamates useful as antiallergy agents

Details Arylhydroxamates useful as antiallergy agents Arylhydroxamates useful as antiallergy agents

1985-04-04

1986-08-19

Evans, J. E.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Radical -xh acid, or anhydride, acid halide or salt thereof...

2605005H, 2605011, 26050111, 514555, 560 20, 562452, C07C 8310, C07C10172, A61K 3119, A61K 31235

Patent

active

046070532

ABSTRACT:
Arylhydroxamates are provided having the structure ##STR1## wherein R.sup.1 is hydrogen, lower alkyl, aryl, lower alkenyl, cycloalkenyl, aralkyl, or ##STR2## wherein n is 1 to 4 and X is hydroxy, alkoxy, amino, C.sub.1 -C.sub.4 -alkylamino or C.sub.1 -C.sub.4 -dialkylamino.

REFERENCES:
patent: 2279560 (1942-04-01), Dietrich
patent: 2279973 (1942-04-01), Dietrich
patent: 3560519 (1971-02-01), Burk et al.
patent: 3900514 (1975-08-01), Chappelow et al.
patent: 3978208 (1976-08-01), Okada
patent: 4528392 (1985-07-01), Musser et al.
Corey et al., "Rationally Designed, Potent Competitive Inhibitors of Leukotriene Biosynthesis", J. Am. Chem. Soc., 1984, 106, 1503-1504.

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