Drug – bio-affecting and body treating compositions – Inorganic active ingredient containing – Phosphorus or phosphorus compound
Reexamination Certificate
2008-04-01
2008-04-01
Kennedy, Sharon E. (Department: 1615)
Drug, bio-affecting and body treating compositions
Inorganic active ingredient containing
Phosphorus or phosphorus compound
C427S002270, C427S002120
Reexamination Certificate
active
10809509
ABSTRACT:
Disclosed is a method for producing a transparent and homogenized polymeric sol of a calcium phosphate compound, containing apatite and having excellent wettability and bioactivity, according to a sol-gel synthesis, and a method for coating the polymeric sol on a metal implant, in which the polymeric sol is coated on the metal implant and then heat-treated to form a dense coated layer strongly bonded to the metal implant. The polymeric sol is obtained by process of preparing a calcium salt solution, containing calcium ethoxide dissolved in organic acid, and a phosphate solution, containing triethyl phosphite or triethyl phosphate dissolved in the organic acid, mixing the calcium salt solution with the phosphate solution to produce a mixed solution, and aging the mixed solution.
REFERENCES:
patent: 5766669 (1998-06-01), Pugh et al.
patent: 5830480 (1998-11-01), Ducheyne et al.
patent: 5861176 (1999-01-01), Ducheyne et al.
patent: 6416774 (2002-07-01), Radin et al.
patent: 6426114 (2002-07-01), Troczynski et al.
patent: 6569489 (2003-05-01), Li
patent: 6667049 (2003-12-01), Janas et al.
patent: 2004/0052861 (2004-03-01), Hatcher et al.
patent: 2005/0031704 (2005-02-01), Ahn
patent: 2006/0141002 (2006-06-01), Liu et al.
patent: 2007/0053814 (2007-03-01), Kobayashi et al.
K.A. Gross et al., “Thin Hydroxyapatite Coatings Via Sol-Gel Synthesis”, Journal of Materials Science: Materials in Medicine, vol. 9 (1998), pp. 839-843.
Dean-Mo Liu, et al., “Water-Based Sol-Gel Synthesis of Hydroxyapatite: Process Development”, Biomaterials, vol. 22 (2001), pp. 1721-1730.
A. Ramila, et al., “Synthesis Routes for Bioactive Sol-Gel Glasses: Alkoxides versus Nitrates”, Chemical Materials, vol. 14, No. 2 (2002) pp. 542-548.
M. J. Filiaggi et al., “Characterization of the Interface in the Plasma-Sprayed HA Coating/Ti-6Al-4V Implant System”, Journal of Biomedical Materials Research, vol. 25, Issue 10, pp. 1211-1229, ABSTRACT.
Chang Bong Soon
Chung Sung Soo
Hong Kug Sun
Kim Jin Young
Lee Choon Ki
Kennedy Sharon E.
Rosenberg , Klein & Lee
Seoul National University Industry Foundation
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