Carrier-reporter bead assemblies

Details Carrier-reporter bead assemblies Carrier-reporter bead assemblies

2008-03-04

2008-03-04

Shibuya, Mark L. (Department: 1639)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

C506S041000

Reexamination Certificate

active

09554376

ABSTRACT:
An assembly of a carrier having one or more reporter beads non-covalently attached thereto which may be used in relation to oligomer libraries. The oligomer libraries may be formed by a combinatorial split-process-recombine procedure. The oligomer library comprises a plurality of molecules comprising a multiplicity of different chemical groups. Each reporter bead has a different marker associated therewith to identify the chemical group attached to the carrier as well as to identify the position in sequence of the chemical group relative to other chemical groups in each molecule of the library. The markers are selected from fluorophores, chromophores, bar codes or radioactive or luminescent labels.

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Webster's II New Riverside Dictionary, 1994, Houghton Mifflin Co., Boston, p. 282.
Ferenc Sebestyen et al., “Binary Synthesis of Multicomponent Peptide Mixtures by the Portioning-mixing Technique”,Journal of Peptide Science, vol. 1, 26-30 (1995).
Eugen Campian et al., “Synthesis of Support-Bound Peptides Carrying Color Labels”,Drug Development Research, 33:98-101 (1994).
W. H. Moos et al., “An integrated approach to exploiting molecular diversity”,Med. Chem., pp. 137-142 (1995).

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