Therapeutic agent for keratoconjunctival disorder

Details Therapeutic agent for keratoconjunctival disorder Therapeutic agent for keratoconjunctival disorder

2008-04-15

2008-04-15

Hartley, Michael G. (Department: 1618)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C514S256000, C514S267000

Reexamination Certificate

active

10576719

ABSTRACT:
Object of the present invention is to search a novel pharmaceutical use of 5-[4-(6-methoxy-1-methyl-1H-benzimidazol-2-ylmethoxy)benzyl]thiazolidine-2,4-dione being a condensed heterocyclic compound, or a salt thereof. 5-[4-(6-methoxy-1-methyl-1H-benzimidazol-2-ylmethoxy)benzyl]thiazolidine-2,4-dione or a salt thereof can exert an excellent effect to promote healing in a dry eye model, and is useful as a therapeutic agent for keratoconjunctival disorders such as dry eyes, corneal ulcer, keratitis, conjunctivitis, superficial punctate keratopathy, corneal epithelial defects, conjunctival epithelial defects, keratoconjunctivitis sicca, superior limbic keratoconjunctivitis and filamentary keratitis.

REFERENCES:
patent: 5447946 (1995-09-01), Kurono et al.
patent: 5885997 (1999-03-01), Lohray et al.
patent: 5886014 (1999-03-01), Fujita et al.
patent: 6372750 (2002-04-01), Lohray et al.
patent: 6573268 (2003-06-01), Lohray et al.
patent: 6780992 (2004-08-01), Lohray et al.
patent: 2007/0093514 (2007-04-01), Nakamura et al.
patent: 3-72227 (1991-11-01), None
patent: 8-231549 (1996-09-01), None
patent: 9-295970 (1997-11-01), None
patent: 11-130675 (1999-05-01), None
patent: 2001-039976 (2000-05-01), None
patent: 2001-39976 (2001-02-01), None
patent: 2002-515874 (2002-05-01), None
patent: 2002-220336 (2002-08-01), None
patent: 2002-255854 (2002-09-01), None
patent: 2003-509503 (2003-03-01), None
patent: WO 97/41097 (1997-11-01), None
patent: WO 01/21602 (2001-03-01), None
U.S. Appl. No. 10/576,402, filed Apr. 20, 2006; Confirmation No. 2359.
H. Hosoya, Tonyobyosei Kakumakusho, Atarashi Ganka, 13(6), pp. 845-851 (1996).
K. Kameyama, Tonyobyo Gappeisho to shiteno Ganbyohen, Rinsho to Yakubutsu Chiryo, 21(11), pp. 1089-1092 (2002).
Y. Chikama, “Sen'ensei Kakumaku Johi Kasson, Ganka” 43, pp. 1625-1631 (2001).
Japanese Review of Clinical Ophthalmology, 46, pp. 738-743 (1992).
Ophthalmic Surgery, 5, pp. 719-727 (1992).

Affiliated with

Also associated with

Rating

Therapeutic agent for keratoconjunctival disorder does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Therapeutic agent for keratoconjunctival disorder, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Therapeutic agent for keratoconjunctival disorder will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3922663