Nitrogen-containing bicyclic compounds and drugs containing...

Details Nitrogen-containing bicyclic compounds and drugs containing... Nitrogen-containing bicyclic compounds and drugs containing...

2008-05-27

2008-05-27

Habte, Kahsay T (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C546S018000, C546S146000

Reexamination Certificate

active

10502884

ABSTRACT:
A nitrogen-containing bicyclic compound of formula (I) or a pharmaceutically acceptable salt thereof (wherein the symbols have the same meanings as described in the specification).The compound of formula (I) has an inhibitory activity against PDE7 and it is useful for the prevention and/or treatment of various diseases, i.e. autoimmune diseases (ulcerative colitis, Crohn's disease, rheumatism, psoriasis, multiple sclerosis, collagenosis, etc.), inflammatory diseases (obstructive pulmonary disease, sepsis, pancreatitis, sarcoidosis, nephritis, hepatitis, enteritis, etc.), allergic diseases (asthma, allergic rhinitis, allergic conjunctivitis, seasonal conjunctivitis, atopic dermatitis, etc.), rejection of organ transplants, serious graft versus host disease (GVHD), diabetic disease, osteoporosis, bone fracture, restenosis, atherosclerosis, obesity, ischemic reperfusion injury, depression, Parkinson's disease, dementia, leukemia, etc.

REFERENCES:
patent: 6956033 (2005-10-01), Ogawa et al.
patent: WO 00/68230 (2000-11-01), None
patent: WO 01/74789 (2001-10-01), None
patent: WO 02/10135 (2002-02-01), None
patent: WO 01/98274 (2002-12-01), None
Nakata, Clin. Exp. Immunol. 2002 128: 460 (2002).
Barun et al. Synlett, 2000, No. 5, 653-657.
Glushkov et al. Chemistry of Heterocyclic Compounds, vol. 37, No. 1, 2001.
Glushkov, V.A. et al.,, “Synthesis of Monooximies of 3,3-Dialkyl-3,4,Dihydro-1-Isoquinolyl Aryl Ketones and Diketones,” Chemistry of Heterocyclic Compounds, 2001, vol. 37, No. pp. 103-108, Plenum Publishing Corporation.

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