Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1978-11-30
1981-09-15
Daus, Donald G.
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
546157, 424258, C07D21522, A61K 3147
Patent
active
042898838
ABSTRACT:
Carbostyril compounds represented by the formula (I) ##STR1## wherein R.sub.1 represents a hydrogen atom, an alkyl group or a phenylalkyl group, R.sub.2 represents an alkenyl group, an alkoxyalkyl group, a hydroxyalkyl group, a carboxyalkyl group, an alkylcarbonyl group, a cycloalkylcarbonyl group, an alkylcarbonylalkyl group, an alkoxycarbonylalkyl group, an alkynyl group or a carbamoylalkyl group, R.sub.3 and R.sub.4, which may be the same or different, each represents a hydrogen atom, an alkyl group, a cycloalkyl group, an alkoxyalkyl group, an alkenyl group, a phenylalkyl group, a phenoxyalkyl group or a phenyl group, and the 3,4-bond of the carbostyril nucleus represents a single or double bond, pharmaceutically acceptable salts thereof, and a process for preparing the same.
REFERENCES:
patent: 3910924 (1975-10-01), Tamura et al.
patent: 3953456 (1976-04-01), Nakagawa et al.
patent: 3969507 (1976-07-01), Kohri
patent: 4072683 (1978-02-01), Nakagawa et al.
patent: 4081447 (1978-03-01), Prasad et al.
patent: 4210753 (1980-07-01), Tominaga et al.
Recent Advances in Clinical Pharmacology, Number One, Ed., Turner et al., Churchill Livingstone, Edinburgh, London & New York, 1978, pp. 31-54.
Nakagawa Kazuyuki
Tominaga Michiaki
Tone Hitoshi
Daus Donald G.
Otsuka Pharmaceutical Co. Ltd.
Rivers Diana G.
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