Synthetic method and intermediate for piroxicam

Details Synthetic method and intermediate for piroxicam Synthetic method and intermediate for piroxicam

1980-09-29

1981-09-15

Ford, John M.

Organic compounds -- part of the class 532-570 series

Organic compounds

Chalcogen in the nitrogen containing substituent

C07D27902

Patent

active

042898790

ABSTRACT:
2-Methoxyethyl 4-hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylate 1,1-dioxide is an advantageous ester precursor for piroxicam (4-hydroxy-2-methyl-N-2-pyridyl-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide), an antiinflammatory agent established in medical practice.

REFERENCES:
patent: 3501466 (1970-03-01), Rasmussen
patent: 3591584 (1971-07-01), Lombardino
patent: 3816628 (1974-06-01), Zinnes et al.

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