CASH (Caspase Homologue) with death effector domain,...

Details CASH (Caspase Homologue) with death effector domain,... CASH (Caspase Homologue) with death effector domain,...

2008-09-02

2008-09-02

Spector, Lorraine (Department: 1647)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

C536S023500, C435S320100, C435S325000, C435S007100, C435S071200

Reexamination Certificate

active

11448842

ABSTRACT:
Proteins capable of modulating or mediating the function of MORT-1 are disclosed. Also disclosed are DNA sequences encoding these proteins, the recombinant production of these proteins as well as their use.

REFERENCES:
patent: 6207458 (2001-03-01), Chaudhary et al.
patent: 6242569 (2001-06-01), Shu et al.
patent: 6623938 (2003-09-01), Ni et al.
patent: 2002/0052474 (2002-05-01), Shu et al.
patent: 2002/0095030 (2002-07-01), Tschopp et al.
patent: 2278349 (1998-03-01), None
patent: 2226973 (1998-05-01), None
patent: 0841399 (1998-05-01), None
patent: WO98/44104 (1998-03-01), None
Chinnaiyan et al, “The cell-death machine”,Cur Biol6(5):555-563 (1996).
Han et al., MRIT, a novel death-effector domain-containing protein, interacts with caspases and BcLXL and initiates cell death,Proc. Natl. Acad. Sci, 94:11333-11338 (1997).
Goltsev et al., CASH, a novel caspase homologue with death effector domains,J Biol Chem. 272:19641-19644 (1997).
XP-002071908—Takeda, Human pancreatic islet cDNA, Accession No. C055730,EMBL/GenBank/DDBJ databases, (1996).
XP-002071907—Hillier et al., Homo sapiens cDNA clone, Accession No. AA149562,EMBL/GenBank/DDBJ databases, (1996).
XP-002071906—Hillier et al., Soares senescent fibroblasts nBHSF Homo sapiens cDNA, Accession No. N94588,EMBL/GenBank/DDBJ databases, (1996).
Srinivasula et al., FLAME-1, a novel FADD-like anti-apoptotic molecule that regulates Fas/TNFR1-induced apoptosis,J Biol Chem., 272(30):18542-18545 (1997).
Phillips, The challenge of gene therapy and DNA delivery,J. Pharm Pharmacology, 53:1169-1174 (2001).
Bowie et al., Deciphering the Message in Protein Sequences: Tolerance to Amino Acid Substitutions,Science, 247:1306-1310 (1990).
Wells, Additivity of mutational effects in proteins,Biochemistry, 29:8509-8517 (1990).
Ngo et al., Computational complexity, protein structure prediction, and the levinthal paradox,in The Protein Folding Problem and Tertiary Structure Prediction, 491-495 (1994).
EM Phizicky et al., Microbiological Reviews, Protein-protein interactions: methods for detection and analysis, 59(1):94-123 (1995).

Affiliated with

Also associated with

Rating

CASH (Caspase Homologue) with death effector domain,... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with CASH (Caspase Homologue) with death effector domain,..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and CASH (Caspase Homologue) with death effector domain,... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3913910