Isolated DNA encoding a nitrilase polypeptide, hosts containing,

Chemistry: molecular biology and microbiology – Micro-organism – per se ; compositions thereof; proces of... – Bacteria or actinomycetales; media therefor

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43525232, 43525233, 43525234, 536 232, 536 237, C12N 121, C07H 2104

Patent

active

056353910

ABSTRACT:
The present invention relates to novel polypeptides having a nitrilase activity and to the genetic tools for producing them, namely:

REFERENCES:
patent: 4810648 (1989-03-01), Stalker
Gavini et al, "Genomic and Phenotypic Characterizations . . . " Curr. Microbiol. 21:279-282 (1990).
Kobayashi et al, "Nitrilate from Rhodococcus rhodochrous J1", J. Biol. Chem. 267:20746-20751 (Oct. 1992).
Bartling et al, "Cloning and expression of an Arabidopsis nitrilase . . . " Eur. J. Biochem. 205:417-424 (Apr. 1992).
Kusukawa et al, "Effects of mutations in heat shock genes groES and groEL . . . " EMBO J. 8(11):3517-3521 (1989).
Kobayashi et al, "Nitrilase in biosynthesis of the plant hormone . . . " PNAS 90:247-251.

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