Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2007-10-09
2007-10-09
McKane, Joseph K. (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C514S278000, C544S096000, C544S130000, C546S016000, C546S187000, C548S314700, C548S517000
Reexamination Certificate
active
11107189
ABSTRACT:
The present invention relates to the CGRP antagonists of general formulawherein A and R1to R3are defined as in claim1, the tautomers, the diastereomers, the enantiomers, the hydrates thereof, the mixtures thereof and the salts thereof and the hydrates of the salts, particularly the physiologically acceptable salts thereof with inorganic or organic acids, pharmaceutical compositions containing these compounds, the use thereof and processes for the preparation thereof.
REFERENCES:
patent: 6344449 (2002-02-01), Rudolf et al.
patent: 2003/0236282 (2003-12-01), Hurnaus et al.
patent: 2004/0063735 (2004-04-01), Chaturvedula et al.
patent: 2006/0252931 (2006-11-01), Mueller et al.
patent: WO 03/076432 (2003-09-01), None
patent: WO 03076432 (2003-09-01), None
John J. Mallee, et al; Receptor Activity-modifying Protein 1 Determines the Species Selectivity of Non-peptide CGRP Receptor Antagonists; The Journal of Biological Chemistry; vol. 277, No. 16, Apr. 19, 2002, pp. 14294-14298; The American Society for Biochemistry and Molecular Biology, Inc.
Arndt Kirsten
Doods Henri
Lustenberger Philipp
Mueller Stephan Georg
Rudolf Klaus
Boehringer Ingelheim International GmbH
Devlin Mary-Ellen M.
Kosack Joseph R.
McKane Joseph K.
Morris Michael P.
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