Method of detection of SP-A2 gene variants useful for...

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

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C435S091200, C536S024330

Reexamination Certificate

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10686786

ABSTRACT:
Allele specific primers and probes suitable for detecting allelic variants of human SP-A2 gene for applications such as molecular diagnosis, prediction of an individual's susceptibility, and/or the genetic analysis of SP-A2 gene in a population.

REFERENCES:
Madan et al. (2002) Association of polymorphisms in the collagen region of human SP-A1 and SP-A2 genes with pulmonary tuberculosis in Indian population. Clin. Chem. Lab Med. 40(10): 1002-1008.
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“Isolation and Characterization of the Human Pulmonary Surfactant Apoprotein Gene”, L. Tyler White, et al., Nature, vol. 319, pp. 361-363, 1985.
“Association of Polymorphisms in the Collagen Region ofSP-A2with Increased Levels of Total IgE Antibodies and Eosinophilia in Patients with Allergic Bronchopulmonary Aspergillosis”, Shweta Saxena, et al., J. Allergy Clin. Immunol., vol. 11(5) 1001-1007 (May 2003).
NCBI Sequence Viewer for GenBank Accession No. M30868, (May 1994).
Sequence Revision History for M30868, M30838 and M68519, (1994).
NCBI Sequence Viewer for GenBank Accession No. M68519, (1995).
Kavanagh et al., Br. J. Biomed. Sci (2001) 58: 197-205.
Madan et al., J. Allergy Clin. Immun. (2000) vol. 105, No. 1 part 2, p. S301.
Priyanka et al., J. Allergy Clin. Immun. (1998) vol. 101, No. 1 part 2, p. S78.
Madan et al., J. Clin Invest (2001) 107(4): 467-475.

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