Materials and methods for treating coagulation disorders

Details Materials and methods for treating coagulation disorders Materials and methods for treating coagulation disorders

2007-10-23

2007-10-23

Owens, Amelia (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C514S457000, C549S401000

Reexamination Certificate

active

11467813

ABSTRACT:
The subject invention provides anticoagulant compounds of formula I:and pharmaceutically acceptable salts thereof, wherein R1, R3, n and Ar are as defined herein. The compounds of the subject invention can be used to treat at-risk populations thereby bringing relief of symptoms, improving the quality of life, preventing acute and long-term complications, reducing mortality and treating accompanying disorders. The invention further comprises pharmaceutical compositions comprising the compounds and salts of the invention, as well as methods of using the compounds, salts, and compositions of the invention.

REFERENCES:
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patent: 5686486 (1997-11-01), Tomich et al.
patent: 6864279 (2005-03-01), Druzgala et al.
patent: 2004/0058985 (2004-03-01), Carter
patent: 2004/0220258 (2004-11-01), Druzgala et al.
patent: WO 02/085882 (2002-10-01), None

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