Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2007-08-07
2007-08-07
Stockton, Laura L. (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S363000, C548S128000, C548S129000, C548S139000
Reexamination Certificate
active
10922425
ABSTRACT:
The present invention relates to compounds of the Formulawherein R3, R5, R7, U, X, Y and Z are as defined. Compounds of the Formula I have activity inhibiting production of Aβ-peptide. This invention also relates to pharmaceutical compositions and methods of treating diseases, for example, neurodegenerative diseases, e.g., Alzheimer's disease, in a mammal comprising compounds of the Formula I.
REFERENCES:
patent: 6323315 (2001-11-01), Pettit et al.
patent: WO-2001/81298 (2001-11-01), None
Thompson et al., Current Medicinal Chemistry, Oct. 2002, 9(19), pp. 1751-1762.
Brown, Neurology, Jun. 25, 2002, 58(12), pp. 1720-1725.
Petit et al., CA 134:237837, 2001.
Kershner David L.
Pfizer Inc
Stockton Laura L.
Zelson Steve T.
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