Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2007-08-14
2007-08-14
Balasubramanian, Venkataraman (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C544S283000
Reexamination Certificate
active
10824321
ABSTRACT:
The present invention relates to dihydrofolate reductase inhibitors having an aromatic group and a heteroaromatic group linked by a methylene group; methods of preparation of dihydrofolate reductase inhibitors that include metal mediated cross coupling of an aromatic halide or heteroaromatic halide with an organozinc reagent; and methods of treatment and pharmaceutical compositions that utilize or comprise one or more of such dihydrofolate reductase inhibitors.
REFERENCES:
patent: 3674825 (1972-07-01), Fitton et al.
patent: 6274587 (2001-08-01), Holladay et al.
Snyder et al., J. Med. Liban 48(4): 208-214, 2000.
Broughton et al. Antimicrobial Agents and Chemotherapy, 1348-1355, 1991.
Chen Han
Rosowsky Andre
Balasubramanian Venkataraman
Corless Peter F.
Dana-Farber Cancer Institute
Edwards Angell Palmer & & Dodge LLP
Russett Mark D.
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