Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues
Reexamination Certificate
2007-12-04
2007-12-04
Spector, Lorraine (Department: 1646)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
C530S402000, C536S023500
Reexamination Certificate
active
10192012
ABSTRACT:
The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
REFERENCES:
patent: 5536637 (1996-07-01), Jacobs
Haynes et al., Electrophoresis 1998, vol. 19(11): pp. 1862-1871.
Chen et al., Mol Cell Proteomics 2002, vol. 1(4): pp. 304-313.
Luck et al., Molecular Endocrinology 1991, vol. 5(12): pp. 1880-1886.
Stuart et al., Lancet. 2004, vol. 364(9442): pp. 1343-1360.
Fessler et al., A genomic and proteomic analysis of the activation of the human neutrophil by lipopolysaccharide and its mediation by p38 mitogen-activated protein kinase, J. Biol. Chem. 277(35):31291-31302, Aug. 30, 2002.
Hu et al., Analysis of genomic and proteomic data using advanced literature mining, J. Proteome Res., 2:405-412, Jun. 2003.
Saito-Hisaminato et al., Genome-wide profiling of gene expression in 29 normal human tissues with a cDNA microarray, DNA Res., 9:32, 2002.
Bustin et al., The value of microarray techniques for quantitative gene profiling in molecular diagnostics, Trends in Mol. Med., 8(6):269-272, 2002.
Sagynaliev et al., Web-based data warehouse on gene expression in human colorectal cancer, Proteomics, 5:3066-3078, Aug. 2005.
Anderson et al., A comparison of selecte mRNA and protein abundances in human liver, Electrophoresis 18:533-537, 1997.
Haviv et al., DNA microarray for assessing ovarian cancer gene expression, Mol. Cell. Endocrinol. 191:121-126, 2002.
Greenbaum et al., Comparing protein abundance and mRNA expression levels on a genomic scale, Genome Biol. 4:117.1-117.8, 2003.
Gygi et al., Correlation between protein and mRNA abundances in yeast, Mol. Cell. Biol. 19(3):1720-1730, Mar. 1999.
Klein et al Selection for Genes Encoding Secreted Proteins and Receptors Proc. Natl. Acad. Sci. 93,7108-7113 (1996).
Database Search. DNA Sequence Alignments (BLASTN 2 2 1 ;Jul. 12, 2001, NCB).
Database Search Protein Sequence Alignments (BLASTP 2 2 1 (Jul. 12, 2001). NCB.).
Beer et al., Nature Medicine 8(8):816-824 (2002).
Orntoft et al., Mol. and Cell. Proteomics, 1:37-45 (2002).
Wen-Hsiang, W., et al., “Comparision ofTP53Mutations Identified by Oligonucleotide Microarray and Conventional DNA Sequence Analysis,”Cancer Research—60:2716-2722 (2000).
Golub, T.R., et al., “Molecular Classification of Cancer: Class Discovery and Class Prediction by Gene Expression Monitoring,”Science—286:531-537 (1999).
MAQC Consortium, “The MicroArray Quality Control (MAQC) Project shows inter- and intraplatform reproducibility of gene expression measurements,” Nature Biotechnology 24:1151-1161 (2006).
Abe, N., et al., “An Increased High-Mobility Group A2 Expression Level is Associated with malignant Phenotype in Pancreatic Exocrine Tissue,”Br J Cancer—89(11):2104-9 (2003) Abstract.
Ando, M., et al., “Selective Apoptosis of Natural Killer-Cell Tumours by I-Asparaginase,”Br J Haematol.,—130(6):860-8 (2005) Abstract.
Aust, G., et al., “Human Thyroid Carcinoma Cell Lines and Normal Thyrocytes: Expression and Regulation of Matrix Metalloproteinase Inhibitor-1 Messenger-RNA and Protein,”Thyroid—7(5):713-24 (1997) Abstract.
Barnes, V.L., et al., “Expression of Embryonic Fibronectin Isoform EIIIA Parallels Alpha-Smooth Muscle Actin in Maturing and Diseased Kidney,”J Histochem Cytochem.—47(6):787-98 (1999) Abstract.
Blaschke, V., et al., “Rapid Quantitation of Proinflammatory and Chemoattractant Cytokine Expression in Small Tissue Samples and Monocyte-Derived Dendritic Cells: Validation of a New Real-Time RT-PCR Technology,”J Immunol Methods.—246(1-2):79-90 (2000) Abstract.
Buckley, A.R., et al., “Butyrate-Induced Reversal of Dexamethasone Resistance in Autonomouse Rat Nb2 Lymphoma Cells,”Apoptosis.—2(6):518-28 (1997) Abstract.
Caberlotto, L. et al.,“Alterations in Neuropeptide Y Levels and Y1 Binding Sites in the Flinders Sensitive Line Rats, A Genetic Animal Model of Depression,”Neurosci Lett.—265(3):191-4 (1999) Abstract.
Caberlotto, L., et al., “Neurokinin 1 Receptor and Relative Abundance of the Short and Long Isoforms in the Human Brain,”Eur J Neurosci.—17(9):1736-46 (2003) Abstract.
Choi, D., et al., “Characterization of Cyclin D2 Expression in Human Endometrium,”J Soc Gynecol Investig.—9(1):41-6 (2002) Abstract.
Couvelard, A., et al., “Human Chorionic Gonadotrophin Beta Expression in Malignant Barrett's Oesophagus,”Virchows Arch.—445(3):279-84 (2004) Abstract.
Dagenais, A., et al., “Downregulation of EnaC Activity and Expression by TNF-Alpha in Alveolar Epithelial Cells,”Am J. Physio Lung Cell Mol Physiol.—286(2):L301-11 (2004) Abstract.
De Boer, C.J., et al., “Involement of the CCNDI Gene in Hairy Cell Leukemia,”Ann Oncol.—7(3):251-6 (1996) Abstract.
Debieve, F., et al., “Inhibin and Activin Production and Subunit Expression in Human Placental Cells Cultured in Vitro,”Mol Hum Reprod.—6(8):743-9 (2000) Abstract.
Dong, Z., et al., “Expression of Membrane-Type Matrix Metalloproteinases 4, 5, and 6 in Mouse Corneas Infected withP. aeruginosa,” Invest Opthalmol Vis Sci—42(13):3223- (2001) Abstract.
Duchrow, M., et al., “Assessment of Proliferative Activity in Colorectal Carcinomas by Quantitative Reverse Transcriptase-Polymerase Chain Reaction (RT-PCR),”Cancer Invest.—19(6):588-96 (2001) Abstract.
Dyer, J., et al., “Molecular Characterisation of Carbohydrate Digestion and Absorption in Equine Small Intestine,”Equine Vet J.—34(4):349-58 (2002) Abstract.
Egwuagu, C.E., et al., “Suppressors of Cytokine Signaling Proteins are Differentially Expressed in Th1 and Th2 Cells: Implications for Th Cell Lineage Commitment and Maintenance,”J Immunol.—168(7):3181-7 (2002) Abstract.
El-Ghrably, I.A., et al., “Intravitreal Invading Cells Contribute to Vitreal Cytokine Milieu in Proliferative Vtreoretinopathy,”Br J Opthalmol.—85(4):461-70 (2001) Abstract.
Eleore, L., et al., “Modulation of the Glutamatergic Receptors (AMPA and NMDA) and of Glutamate Vesicular Transporter 2 in the Rat Facial Nucleus after Axotomy,”Neuroscience—136(1):147-60 (2005) Abstract.
Forsberg, H., et al., “Altered Levels of Scavenging Enzymes in Embryos Subjected to Diabetic Environment,”Free Radic Res.—24(6):451-9 (1996) Abstract.
Freyschuss, B., et al., “Induction of the Estrogen Receptor by Growth Hormone and Glucocorticoid Substitution in Primary Cultures of Rat Hepatocytes,”Endocrinology—133(4):1548-54 (1993) Abstract.
Fu, K., et al., “Cyclin D1-Negative Mantle Cell Lymphoma: A Clinocopathologic Study Based on Gene Expression Profiling,”Blood—106(13):4315-21 (2005) Abstract.
Fuchs, A.R., et al., “Oxytocin Receptors in Bovine Cervix: Distrubution and Gene Expression During the Estrous Cycle,”Biol Reprod.—54(3):700-8 (1996) Abstract.
Furuta, J., et al., “Silencing of the Thrombomodulin Gene in Human Malignant Melanoma,”Melanoma Res.—15(1):15-20 (2005) Abstract.
George, J., et al., “Pre-translational Regulation of Cytochrome P450 Genes is Responsible for Disease-Specific Changes of Individual P450 Enzymes Among Patients with Cirrhosis,”Biochem Pharmacol.—49(7):873-81 (1995) Abstract.
Giroux, M., et al., “Cyclooxygenase-2 Expression in Macrophages: Modulation by Protein Kinase C-alpha,”J immunol.—165(7):3985-91 (2000) Abstract.
Godbout, R., et al., “Overexpressio
Genentech Inc.
Kaufman Claire M.
Spector Lorraine
LandOfFree
PRO9742 polypeptides does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with PRO9742 polypeptides, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and PRO9742 polypeptides will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3882612