Substituted thiazolopyrimidines as xanthine oxidase inhibitors

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Phosphorus containing other than solely as part of an...

Reexamination Certificate

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C514S260100, C514S263300, C514S263400, C514S263100, C514S301000, C514S302000, C514S303000, C514S367000, C514S375000, C514S394000, C544S255000, C544S244000, C544S276000, C544S265000, C544S264000, C544S277000, C546S021000, C546S118000, C546S114000, C546S115000, C548S112000, C548S303100, C548S153000, C548S152000, C548S218000, C548S224000

Reexamination Certificate

active

10495844

ABSTRACT:
The invention relates to compounds of the following formula (I) or their salts:in which R1represents OR4or others, in which R4is an alkyl group having 1-8 carbon atoms which may have a substituent or the like; R2is halogen, nitro, cyano, carboxyl, or the like; R3is hydrogen, halogen, hydroxyl, amino, carboxyl, or the like; X is NR11, oxygen, or sulfur, in which R11is hydrogen, or an alkyl group having 1-8 carbon atom which may have a substituent; and each of Y and Z is CR12or nitrogen, in which R12has the same meaning as R3above, and a xanthine oxidase inhibitor containing the compound as an active ingredient.

REFERENCES:
patent: 4038396 (1977-07-01), Shen et al.
patent: 4299834 (1981-11-01), Austel et al.
patent: 2 119377 (1983-04-01), None
patent: 03-258770 (1991-11-01), None
patent: WO 01/96299 (2001-12-01), None
patent: WO 01/96336 (2001-12-01), None
patent: WO 03/074516 (2003-09-01), None

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