Human interferon-inducible protein

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

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514 2, 536 231, 536 243, 536 253, 435 701, 4351721, 530350, C07K 100, A01K 3718, C07H 2102, C07H 2104

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057926263

ABSTRACT:
The present invention provides a novel human interferon-inducible protein (HIFI) and the polynucleotides which identify and encode HIFI. The invention provides for genetically engineered expression vectors and host cells comprising the nucleic acid sequence encoding HIFI and for a method for producing the protein. The invention also provides compositions containing HIFI.

REFERENCES:
Hardman, J.G., et al., "The Pharmacological Basis of Therapeutics", pp. 1211-1215 (1996).
Kato, T., et al., "Interferon-Inducible Gene Expression in Chimpanzee Livber Infected with Hepatitis C Virus", Virology, 190:856-860 (1992).
Kelly, J.M., et al., "Characterization of a human gene inducible by .alpha.-and .beta.-interferons and its expression in mouse cells", EMBO J, 5:1601-1606 (1986).
Rasmussen, U.B., et al., "Indentification of a New Interferon-.alpha.-inducible Gene (p27) on Human Chromosome 14q32 and Its Expression in Breast Carcinoma", Cancer Res., 53:4096-4101 (1993).

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