Methods and compositions for inhibiting tumor growth

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Cyclopentanohydrophenanthrene ring system doai

Reexamination Certificate

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C552S510000

Reexamination Certificate

active

10545143

ABSTRACT:
The present invention relates to novel betulinic acid derivatives with increased activity for the treatment of carcinomas and HIV diseases, a method for preparing such novel betulinic acid derivatives as well as their use as pharmaceuticals.

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patent: WO 01/18029 (2001-03-01), None
patent: WO 02/091858 (2002-11-01), None
Greene and Wuts, “Chapter 2: Protection for the Hydroxyl Group, Including 1,2- and 1,3-Diols,” In: Protective Groups in Organic Synthesis3rdEd., John Wiley&Sons, Inc., pp. 17-245, 1999.
Greene and Wuts, “Chapter 7: Protection for the Amino Group,” In: Protective Groups in Organic Synthesis3rdEd., John Wiley&Sons, Inc., pp. 494-653, 1999.
Sigma, Cat. No. H-107. 2006.
Sigma, Cat. No. H-125. 2006.
Wermuth, “The Practice of Medicinal Chemistry,” Academic Press, San Diego CA, pp. 756-776, 1996.

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