Method for producing recombinant proteins

Details Method for producing recombinant proteins Method for producing recombinant proteins

2007-11-13

2007-11-13

Nickol, Gary B. (Department: 1646)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

C435S070100, C435S235100, C435S325000, C435S335000, C435S383000, C435S384000, C435S320100, C435S069700, C436S547000, C530S351000, C530S387100

Reexamination Certificate

active

10233250

ABSTRACT:
A method for producing recombinant proteins, preferably fusion proteins comprising an Fc portion of an immunoglobulin molecule, more preferably fusion proteins comprising an extracellular domain of a tumor necrosis factor receptor fused to the Fc portion of an immunoglobulin molecule, is disclosed. The method of the present invention allows a reduction of misfolding of the protein, thereby giving rise to a higher yield of the desired protein.

REFERENCES:
patent: 4216203 (1980-08-01), Johnston
patent: 4357422 (1982-11-01), Giard
patent: 5196523 (1993-03-01), Lee
patent: 5395760 (1995-03-01), Smith et al.
patent: 5705364 (1998-01-01), Etcheverry
patent: 5721121 (1998-02-01), Etcheverry
patent: 5976833 (1999-11-01), Furukawa et al.
patent: 6716602 (2004-04-01), Andersen et al.
Mather et al,Large Scale Mammalian Cell Culture Technology, Marcel Dekker, Inc., New York and Basel, pp. 161-177, (1990).
Takagi et al,Appl. Microbiol. Biotechnol., 41:565-570 (1994).
Bloemkolk et al,Biotechn. and Bioeng., 40:427-431 (1992).
Sureshkumar et al,Biotechn. and Bioeng., 37:292-295 (1991).
Reuveny et al,J. of Immunol. Methods, 86:53-59 (1986).
Kamech et al,Experimental Cell Research, 162:326-334 (1986).
Oh et al,Biotechn. And Bioeng., 42:601-610 (1993).
Chotigeat et al,Cytotechnology, 15:217-221 (1994).
Palermo et al,J. of Biotech., 19:35-48 (1991).
Weidemann et al,Cytotechnology, 15:111-116 (1994).
Moore et al,Cytotechnology, 23:47-54 (1997).
Guppy et al,Vox Sang, 62:70-75 (1992).
Tsao et al,Biotechn. And Bioeng., 40:1190-1196 (1992).
Morris et al,Animal Cell Technology, pp. 529-534 (1997).
Kaptein et al,Gene Ther., 4(2):172-176 (1997)—Abstract.
Jordan et al,Nucleic Acids Res., 24(4):596-601 (1996)—Abstract.
Kirinaka et al,Appl. Microbiol. Biotechnol., 41(5):591-591 (1994)—Abstract.
Yu et al,Archives of Dermatological Res., 289(6):352-359 (1997)—Abstract.

Affiliated with

Also associated with

Rating

Method for producing recombinant proteins does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method for producing recombinant proteins, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for producing recombinant proteins will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3865494