Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2007-08-07
2007-08-07
McKane, Joseph K. (Department: 1626)
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
C564S192000, C564S182000, C560S132000, C560S129000, C514S601000, C514S663000, C514S571000
Reexamination Certificate
active
11303119
ABSTRACT:
The invention is concerned with novel hexafluoroisopropanol substituted cyclohexane derivatives of formula (I)wherein R1to R4, X, m and n are as defined in the description and in the claims, as well as physiologically acceptable salts and esters thereof. These compounds bind to LXR alpha and LXR beta and can be used as medicaments.
REFERENCES:
patent: WO 02/058690 (2002-08-01), None
patent: WO 03/090732 (2003-11-01), None
patent: WO 03/099769 (2003-12-01), None
Willy et al., Genes Dev. 1995, 9:1033-45.
Song et al., Proc Natl Acad Sci USA. 1994, 91:10809-13.
Miller NE., Lipids 1978, 13:914-9.
Gordon et al., Am J Med. 1977, 62:707-14.
Lund et al., Arterioscler. Thromb. Vasc. Biol. 2003, 23:1169-77.
Joseph and Tontonoz, Curr. Opin. Pharmacol. 2003, 3:192-7.
Cao et al., J Biol Chem. 2003, 278:1131-6.
Dehmlow Henrietta
Kuhn Bernd
Masciadri Raffaello
Panday Narendra
Ratni Hasane
Barker Michael P.
Hoffman-La Roche Inc.
Johnston George W.
McKane Joseph K.
Megerditchian Samuel H.
LandOfFree
Hexafluoroisopropanol substituted cyclohexane derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Hexafluoroisopropanol substituted cyclohexane derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Hexafluoroisopropanol substituted cyclohexane derivatives will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3865104