Drug – bio-affecting and body treating compositions – Whole live micro-organism – cell – or virus containing – Genetically modified micro-organism – cell – or virus
Patent
1995-06-07
1998-08-11
Degen, Nancy
Drug, bio-affecting and body treating compositions
Whole live micro-organism, cell, or virus containing
Genetically modified micro-organism, cell, or virus
4351723, 4353201, 435366, 536 235, A01N 6300
Patent
active
057924538
ABSTRACT:
The transgene-inserted replication-deficit adenovirus vector is effectively used in in vivo gene therapy for peripheral vascular disease and heart disease, including myocardial ischemia, by a single intra-femoral artery or intracoronary injection directly conducted deeply in the lumen of the one or both femoral or coronary arteries (or graft vessels) in an amount sufficient for transfecting cells in a desired region.
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Dillmann Wolfgang H.
Giordano Frank J.
Hammond H. Kirk
Degen Nancy
The Regents of the University of California
Yucel Irem
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