Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Oxidoreductase
Reexamination Certificate
2007-10-02
2007-10-02
Saidha, Tekchand (Department: 1652)
Chemistry: molecular biology and microbiology
Enzyme , proenzyme; compositions thereof; process for...
Oxidoreductase
C435S183000, C435S252300, C435S320100, C435S810000, C536S023200
Reexamination Certificate
active
10769481
ABSTRACT:
The invention relates to a modified IMPDH polypeptide wherein the IMPDH polypeptide has a histidine tag and where the subdomain of the IMPDH polypeptide is modified so that the rate stability of the histidine-tagged, modified IMPDH polypeptide is maintained relative to the wild-type IMPDH polypeptide. The invention also relates to a method, nucleic acid molecules, vectors, and host cells for producing such a histidine-tagged, modified IMPDH polypeptide, and to kits comprising the histidine-tagged, modified IMPDH polypeptide.
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Dorn Allan R.
Rugaber Janice E.
Amick Marilyn L.
Fronda Christian L.
Roche Diagnostics Operations Inc.
Roche Diagnostics Operations Inc.
Saidha Tekchand
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