Benzothiepine ileal bile acid transport inhibitors

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C549S012000

Reexamination Certificate

active

10489010

ABSTRACT:
The present invention relates to compounds of formula (I) wherein variable groups are as defined within; pharmaceutically acceptable salts, solvates, solvates of such salts and prodrugs thereof and their use as ileal bile acid transport (IBAT) inhibitors for the treatment of hyperlipidaemia. Processes for their manufacture and pharmaceutical compositions containing them are also described

REFERENCES:
patent: 6346527 (2002-02-01), Takenaka et al.
patent: 6355672 (2002-03-01), Yasuma et al.
patent: 6906058 (2005-06-01), Starke et al.
patent: 6943189 (2005-09-01), Keller et al.
patent: 7019023 (2006-03-01), Frick et al.
patent: 7125864 (2006-10-01), Starke et al.
patent: 7132416 (2006-11-01), Starke et al.
patent: 2002/0142054 (2002-10-01), Marlett et al.
patent: 19825804 (1999-12-01), None
patent: 0372542 (1990-06-01), None
patent: 0 864 582 (1998-09-01), None
patent: 2262888 (1993-07-01), None
patent: 93/16055 (1993-08-01), None
patent: 94/18183 (1994-08-01), None
patent: 94/18184 (1994-08-01), None
patent: 96/05188 (1996-02-01), None
patent: 96/08484 (1996-03-01), None
patent: 96/16051 (1996-05-01), None
patent: 97/33882 (1997-09-01), None
patent: 98/38182 (1998-09-01), None
patent: 98/40375 (1998-09-01), None
patent: 99/01149 (1999-01-01), None
patent: 99/32478 (1999-07-01), None
patent: 99/35135 (1999-07-01), None
patent: 99/64409 (1999-12-01), None
patent: 99/64410 (1999-12-01), None
patent: 00/01687 (2000-01-01), None
patent: 00/38725 (2000-07-01), None
patent: 00/38726 (2000-07-01), None
patent: 00/38727 (2000-07-01), None
patent: 00/38728 (2000-07-01), None
patent: 00/38729 (2000-07-01), None
patent: 00/47568 (2000-08-01), None
patent: 00/61568 (2000-10-01), None
patent: 00/62810 (2000-10-01), None
patent: 01/60807 (2001-08-01), None
patent: 01/66533 (2001-09-01), None
patent: 01/68096 (2001-09-01), None
patent: 01/68637 (2001-09-01), None
patent: 02/08211 (2002-01-01), None
patent: 02/32428 (2002-04-01), None
patent: 02/50051 (2002-06-01), None
patent: 02/053548 (2002-07-01), None
patent: 03/020710 (2003-03-01), None
patent: 03/022286 (2003-03-01), None
patent: 03/022825 (2003-03-01), None
patent: 03/061663 (2003-07-01), None
patent: 03/091232 (2003-11-01), None
patent: 03/106482 (2003-12-01), None
patent: 2004/006899 (2004-01-01), None
patent: 2004/076430 (2004-09-01), None
patent: 2004/089350 (2004-10-01), None
Govers et al., Journal of Lipid Research, 35(5), 1994, pp. 741-748.
Higaki et al., Arteriosclerosis, Thrombosis, and Vascular Biology, 18(8), 1998, pp. 1304-1311.
Ishibashi et al., Journal of Clinical Investigation, 92(2), 1993, pp. 883-893.
Lewis et al., Journal of Lipid Research, 36, 1995, pp. 1098-1105.
Plump et al., Cell, (71), 1992, pp. 343-353.
Schiller, Alimentary Pharmacology and Therapeutics, 15(6), 2001, pp. 749-763.
Sprong et al., J. Nutrition (US), 132(6), 2002, pp. 1269-1274.
Van Tilburg et al., Gastroenterology, 98(1), 1989, pp. 25-32.
Welberg et al., Scandinavian J. Gastroenterology Suppl Norway, 188, 1991, pp. 52-59.
U.S. Appl. No. 10/399,336, filed Sep. 16, 2003, Starke et al.
U.S. Appl. No. 10/451,262, filed Jun. 20, 2003, Starke et al.
U.S. Appl. No. 10/488,540, filed Jul. 23, 2004, Starke et al.
U.S. Appl. No. 10/502,355, filed Feb. 4, 2005, Lindqvist.
U.S. Appl. No. 10/511,984, filed Oct. 21, 2004, Starke et al.
U.S. Appl. No. 10/518,010, filed Dec. 14, 2004, Starke et al.
U.S. Appl. No. 10/520,939, filed Jan. 12, 2005, Anderberg et al.
U.S. Appl. No. 10/546,005, filed Aug. 18, 2005, Starke et al.
U.S. Appl. No. 10/551,999, filed Oct. 4, 2005, Abrahamsson et al.

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