Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2007-06-05
2007-06-05
Lambkin, Deborah C. (Department: 1625)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C549S012000
Reexamination Certificate
active
10489010
ABSTRACT:
The present invention relates to compounds of formula (I) wherein variable groups are as defined within; pharmaceutically acceptable salts, solvates, solvates of such salts and prodrugs thereof and their use as ileal bile acid transport (IBAT) inhibitors for the treatment of hyperlipidaemia. Processes for their manufacture and pharmaceutical compositions containing them are also described
REFERENCES:
patent: 6346527 (2002-02-01), Takenaka et al.
patent: 6355672 (2002-03-01), Yasuma et al.
patent: 6906058 (2005-06-01), Starke et al.
patent: 6943189 (2005-09-01), Keller et al.
patent: 7019023 (2006-03-01), Frick et al.
patent: 7125864 (2006-10-01), Starke et al.
patent: 7132416 (2006-11-01), Starke et al.
patent: 2002/0142054 (2002-10-01), Marlett et al.
patent: 19825804 (1999-12-01), None
patent: 0372542 (1990-06-01), None
patent: 0 864 582 (1998-09-01), None
patent: 2262888 (1993-07-01), None
patent: 93/16055 (1993-08-01), None
patent: 94/18183 (1994-08-01), None
patent: 94/18184 (1994-08-01), None
patent: 96/05188 (1996-02-01), None
patent: 96/08484 (1996-03-01), None
patent: 96/16051 (1996-05-01), None
patent: 97/33882 (1997-09-01), None
patent: 98/38182 (1998-09-01), None
patent: 98/40375 (1998-09-01), None
patent: 99/01149 (1999-01-01), None
patent: 99/32478 (1999-07-01), None
patent: 99/35135 (1999-07-01), None
patent: 99/64409 (1999-12-01), None
patent: 99/64410 (1999-12-01), None
patent: 00/01687 (2000-01-01), None
patent: 00/38725 (2000-07-01), None
patent: 00/38726 (2000-07-01), None
patent: 00/38727 (2000-07-01), None
patent: 00/38728 (2000-07-01), None
patent: 00/38729 (2000-07-01), None
patent: 00/47568 (2000-08-01), None
patent: 00/61568 (2000-10-01), None
patent: 00/62810 (2000-10-01), None
patent: 01/60807 (2001-08-01), None
patent: 01/66533 (2001-09-01), None
patent: 01/68096 (2001-09-01), None
patent: 01/68637 (2001-09-01), None
patent: 02/08211 (2002-01-01), None
patent: 02/32428 (2002-04-01), None
patent: 02/50051 (2002-06-01), None
patent: 02/053548 (2002-07-01), None
patent: 03/020710 (2003-03-01), None
patent: 03/022286 (2003-03-01), None
patent: 03/022825 (2003-03-01), None
patent: 03/061663 (2003-07-01), None
patent: 03/091232 (2003-11-01), None
patent: 03/106482 (2003-12-01), None
patent: 2004/006899 (2004-01-01), None
patent: 2004/076430 (2004-09-01), None
patent: 2004/089350 (2004-10-01), None
Govers et al., Journal of Lipid Research, 35(5), 1994, pp. 741-748.
Higaki et al., Arteriosclerosis, Thrombosis, and Vascular Biology, 18(8), 1998, pp. 1304-1311.
Ishibashi et al., Journal of Clinical Investigation, 92(2), 1993, pp. 883-893.
Lewis et al., Journal of Lipid Research, 36, 1995, pp. 1098-1105.
Plump et al., Cell, (71), 1992, pp. 343-353.
Schiller, Alimentary Pharmacology and Therapeutics, 15(6), 2001, pp. 749-763.
Sprong et al., J. Nutrition (US), 132(6), 2002, pp. 1269-1274.
Van Tilburg et al., Gastroenterology, 98(1), 1989, pp. 25-32.
Welberg et al., Scandinavian J. Gastroenterology Suppl Norway, 188, 1991, pp. 52-59.
U.S. Appl. No. 10/399,336, filed Sep. 16, 2003, Starke et al.
U.S. Appl. No. 10/451,262, filed Jun. 20, 2003, Starke et al.
U.S. Appl. No. 10/488,540, filed Jul. 23, 2004, Starke et al.
U.S. Appl. No. 10/502,355, filed Feb. 4, 2005, Lindqvist.
U.S. Appl. No. 10/511,984, filed Oct. 21, 2004, Starke et al.
U.S. Appl. No. 10/518,010, filed Dec. 14, 2004, Starke et al.
U.S. Appl. No. 10/520,939, filed Jan. 12, 2005, Anderberg et al.
U.S. Appl. No. 10/546,005, filed Aug. 18, 2005, Starke et al.
U.S. Appl. No. 10/551,999, filed Oct. 4, 2005, Abrahamsson et al.
Blomberg David
Dahlstrom Mikael Ulf Johan
Starke Ingemar
AstraZeneca AB
Lambkin Deborah C.
Morgan & Lewis & Bockius, LLP
LandOfFree
Benzothiepine ileal bile acid transport inhibitors does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Benzothiepine ileal bile acid transport inhibitors, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Benzothiepine ileal bile acid transport inhibitors will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3856956