Surgery – Diagnostic testing – Measuring or detecting nonradioactive constituent of body...
Reexamination Certificate
2007-02-20
2007-02-20
Winakur, Eric F. (Department: 3768)
Surgery
Diagnostic testing
Measuring or detecting nonradioactive constituent of body...
C600S323000, C600S324000
Reexamination Certificate
active
10987505
ABSTRACT:
Disclosed is a pulmonary artery catheter (“PAC”) that is used in determining myocardial oxygen consumption. Myocardial oxygen consumption is of critical importance because decreased myocardial energy utilization during acute illness may lead to tissue hypoperfusion, multiple organ failure, and eventually death. The inventor has discovered that myocardial oxygen consumption is a function of the difference in oxygen levels in atrial and mixed venous blood. The invention has further discovered that differences in lactate, glucose or any other measurable blood concentration metabolite in atrial or superior vena cava and mixed venous blood can also be used in determining myocardial oxygen consumption.
REFERENCES:
patent: 3995623 (1976-12-01), Blake et al.
patent: 4684245 (1987-08-01), Goldring
patent: 5435308 (1995-07-01), Gallup et al.
patent: 5788647 (1998-08-01), Eggers
patent: 6299583 (2001-10-01), Eggers et al.
patent: 6532378 (2003-03-01), Saksena et al.
patent: 7010337 (2006-03-01), Furnary et al.
Lakhmir S. Chawla, MD, et al., “Lack of Equivalence Between Central and Mixed Venous Oxygen Saturation” Dec. 6, 2004, pp. 1891-1896, Chest 126.
Konrad Reinhart, et al., “Continous central venous and pulmonary artery oxygen saturation monitoring in the critically ill” Intensive Care Med (2004) 30: pp. 1572-1578
Emanuel Rivers, MD,MPH., et al., “Early Goal-Directed Therapy in the Treatment of Severe Sepsis and Septic Shock” Nov. 8, 2001, pp. 1368-1377, N Engl J Med, vol. 345, No. 19.
Michael D. Crittenden, MD, “Intraoperative Metabolic Monitoring of the Heart: I. Clinical Assessment of Coronary Sinus Metabolites”, 2001; 72:S2220-6, The Society of Thoracic Surgeons Published by Elsevier Science Inc.
Darrel P. Francis, MA, MRCP, et al., “Oxygenation in Patients with a Functionality Univentricular Circulation and complete Mixing of Blood” 1999 pp. 2198-2203, American Heart Association, Inc.
Gordon R. Bernard, MD, et al., “Pulmonary Artery Catheterization and Clinical Outcomes”, May 17, 2000, pp. 2559-2577, JAMA, vol. 283, No. 19.
Holland & Knight LLP
Lin Jack
Moran John P.
Winakur Eric F.
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