5-Aryl-substituted-2,3-dihydro-imidazo(1,2-a)furo- and thieno py

Details 5-Aryl-substituted-2,3-dihydro-imidazo(1,2-a)furo- and thieno py 5-Aryl-substituted-2,3-dihydro-imidazo(1,2-a)furo- and thieno py

1990-12-04

1992-08-25

Richter, Johann

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

5142285, 5142332, 514255, 514293, A61K 3138, A61K 3141

Patent

active

051419327

ABSTRACT:
The invention discloses certain 5-aryl-substituted-2,3-dihydro-imidazo[1,2-a]furo- and thieno pyridines useful as PAF receptor antagonists and for treating tumors, pharmaceutical compositions containing said compounds as an active ingredient thereof and a method of using such compositions for inhibiting PAF-mediated bronchoconstriction and extravasation, for controlling hyperreactive airways, for protecting against endotoxin-induced hypotension and death and for treating tumors.

REFERENCES:
patent: 4100165 (1978-07-01), Houlihan
patent: 4101553 (1981-07-01), Houlihan
patent: 4279912 (1981-07-01), Ages et al.

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