Synthetic vasoactive intestinal peptide analogs

Details Synthetic vasoactive intestinal peptide analogs Synthetic vasoactive intestinal peptide analogs

1989-06-30

1992-08-25

Cashion, Jr., Merrell C.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 20, 530324, 530325, 930170, 930DIG821, 930DIG820, 930DIG800, A61K 3702, C07K 710

Patent

active

051419246

ABSTRACT:
Vasoactive intestinal peptide analogs containing substitutions of appropriately selected amino acids at specific positions of the VIP molecule.

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patent: 4822774 (1989-04-01), Ito et al.
patent: 4835252 (1989-05-01), Musso et al.
Biochemical & Biophysical Research Comm. vol. 121, No. 2, 1984, pp. 493-498.
Peptides, Chemistry & Biology, Marshall, pp. 440-443, 1988.
Schaaper et al., Chem. Abs. vol. 100, No. 19, 156971m, (1984) [Recl., J.R. Neth. Chem. Soc. 103(1) pp. 17-22].
Musso et al., Biochemistry, vol. 27, pp. 8174-8181, (1988).
Barnes, Pharmac. Ther., vol. 36, pp.119-129 (1988).
Pandol et al., "VIP Receptor Antagonist", Rapid Communication, G553-G557, (1986).
Tachibana et al., Peptide Chemistry, pp. 481-486, (1987).

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