Compositions and methods for generating antigen-binding units

Details Compositions and methods for generating antigen-binding units Compositions and methods for generating antigen-binding units

2007-02-20

2007-02-20

Helms, Larry R. (Department: 1643)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

C435S005000, C435S007100, C435S069600, C435S069700, C435S254200, C435S320100, C435S325000, C435S465000, C530S350000, C530S371000, C530S387300, C530S388220, C530S388750, C536S023100, C536S023200, C536S023400, C536S023500, C536S063000

Reexamination Certificate

active

10226949

ABSTRACT:
The present invention provides non-single-chain antigen-binding units that is stabilized by leucine zipper sequences. The experimental design is particularly useful for generating and screening for Nsc Abus that remain the binding capabilities to their respective antigens within a cell. The present invention also provides recombinant polynucleotides, host cells and kits comprising the vectors. Further provided by the invention are methods of using the subject vectors.

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