Polymorphic forms of a GABA A agonist

Details Polymorphic forms of a GABA A agonist Polymorphic forms of a GABA A agonist

2007-08-28

2007-08-28

Seaman, D. Margaret (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C546S116000

Reexamination Certificate

active

11045768

ABSTRACT:
Two new crystalline monhydrates and two new crystalline anhydrates of gaboxadol are disclosed together with methods for preparing them.

REFERENCES:
patent: 4278676 (1981-07-01), Krogsgaard-Larsen
patent: 4301287 (1981-11-01), Krogsgaard-Larsen
patent: 4315934 (1982-02-01), Christensen
patent: 4362731 (1982-12-01), Hill
patent: 5929065 (1999-07-01), Lancel
patent: 0000338 (1978-06-01), None
patent: WO 02/40009 (2002-05-01), None
patent: WO 02/094225 (2002-11-01), None
patent: WO 2004/112786 (2004-12-01), None
patent: WO 2005/023256 (2005-03-01), None
patent: WO 2005/023820 (2005-03-01), None
patent: WO 2005/073237 (2005-08-01), None
patent: WO 2006/013397 (2006-02-01), None
patent: WO 2006/053556 (2006-05-01), None
patent: WO 2006/083682 (2006-08-01), None
patent: WO 2006/102093 (2006-09-01), None
patent: WO 2006/118897 (2006-11-01), None
Lipkowitz et al. Journal of Molecular Structure, 195 (1989) 65-77.
Soren Munk Madsen, “Quantitative Determination of the Gamma-Aminobutyric Acid Agonist, 4,5,6,7-Tetrahydroisoxazolo[5,4-c]pyridine-3-OL, in Serum by High-Performance Liquid Chromatography”,Journal of Chromatography, p. 209-218, 274, (1983).
Soren Munk Madsen, “Pharmacokinetics of the Gamma-Aminobutyric Acid Agonist THIP (Gaboxadol) Following Intramuscular Administration to Man, with Oberservations in Dog”,Acta Pharmacol. et toxicol, p. 353-357, 53, (1983).
Richard Huckle, “Gaboxadol Lundbeck/Merck”,Current Opinion in Investigational Drugs, p. 766-773, 5(7), 2004.

Affiliated with

Also associated with

Rating

Polymorphic forms of a GABA A agonist does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Polymorphic forms of a GABA A agonist, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Polymorphic forms of a GABA A agonist will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3849889