Method of detecting and preventing Alzheimer's disease,...

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

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Reexamination Certificate

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ABSTRACT:
A method of detecting Alzheimer's disease includes detecting a disruption or alteration in normal sub-cellular distribution of G-protein receptor kinases (GRKs), particularly GRK2 and GRK5. The disruption is caused by abnormal accumulation of soluble β-amyloid. The prevention or suppression of the disease progression at prodromal or early stages includes correction of GRK dysfunction.

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patent: 6110693 (2000-08-01), Barak et al.
patent: WO 99/27944 (1999-06-01), None
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