Interferon-like protein Zcyto21

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Lymphokines – e.g. – interferons – interlukins – etc.

Reexamination Certificate

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Details

C435S069510, C435S070100, C435S325000, C424S085400

Reexamination Certificate

active

10927815

ABSTRACT:
The present invention relates to polynucleotide and polypeptide molecules for Zcyto21, an interferon-like protein, which is most closely related to interferon-α at the amino acid sequence level. The present invention also includes antibodies to the Zcyto21 polypeptides, and methods of using the polynucleotides and polypeptides.

REFERENCES:
patent: 0 032 124 (1981-07-01), None
patent: 02/092762 (2002-11-01), None
patent: 03/066002 (2003-08-01), None
Adams et al., Accession No. T07139, 1993.
DOE Joint Genome Institute Stanford Human Genome Center, Accession No. AC011445, 1999.
Muzney et al., Accession No. AC0118477, 1999.
Sanger Centre Search Results, Accession No. AC011445, 2001.
University of California Santa Cruz database using Softberry, Inc. gene prediction software, Accession No. C19001084, 2001.
Scott et al., “The Pendred syndrome gene encodes a chloride-iodide transport protein,”Nature Genetics, 21:440-443, 1999.
Korba et al., “A cell culture assay for compounds which inhibit hepatitis B virus replication,”Antiviral Research 15:217-228, 1991.
Korba et al., “Use of a standardized cell culture assay to assess activities of nucleoside analogs against hepatitis B virus replication,”Antiviral Research 19:55-70, 1992.
Kotenko et al., “IFN-λs mediate antiviral protection through a distinct class II cytokine receptor complex,”Nat. Immunol. 4(1):69-77, 2003.
Sheppard et al., “IL-28, IL-29 and their class II cytokine receptor IL-28R,”Nat. Immunol. 4(1):63-68, 2003.
Brack et al., “Molecular analysis of the human interferon-α gene family,”Gene 15:379-394, 1981.

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