Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing alpha or beta amino acid or substituted amino acid...
Reexamination Certificate
2007-11-13
2007-11-13
Prouty, Rebecca E. (Department: 1652)
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing alpha or beta amino acid or substituted amino acid...
C435S252100, C435S245000, C435S252300, C435S252330
Reexamination Certificate
active
11265288
ABSTRACT:
The present invention provides a method for producing L-glutamic acid by fermentation, by culturing in a liquid medium a microorganism that can metabolize a carbon source at a specific pH, and wherein said medium contains a carbon source and L-glutamic acid at a saturation concentration, and wherein said microorganism is able to cause accumulation of an amount of L-glutamic acid in a liquid medium having said pH, wherein said amount exceeds the amount of L-glutamic acid at said saturation concentration when the pH of the medium is controlled so that L-glutamic acid is precipitated, making L-lysine exist in the medium when L-glutaminc acid concentration is lower than the concentration at which natural crystallization of L-glutamic acid occurs, and precipitating the α-form crystals of L-glutamic acid.
REFERENCES:
patent: 3032474 (1962-05-01), Foster
patent: 3220929 (1965-11-01), Kinoshita et al.
patent: 5908768 (1999-06-01), Ono et al.
patent: 6197559 (2001-03-01), Moriya et al.
patent: 6331419 (2001-12-01), Moriya et al.
patent: 6596517 (2003-07-01), Izui et al.
patent: 6653110 (2003-11-01), Sato et al.
patent: 6881861 (2005-04-01), Saitou et al.
patent: 2001/0019836 (2001-09-01), Moriya et al.
patent: 2002/0192772 (2002-12-01), Sato et al.
patent: 2003/0003550 (2003-01-01), Nakamura et al.
patent: 2003/0119153 (2003-06-01), Moriya et al.
patent: 2005/0227334 (2005-10-01), Izui et al.
patent: 0670370 (1995-09-01), None
patent: 0952221 (1999-10-01), None
patent: 0999282 (2000-05-01), None
patent: 1078989 (2001-02-01), None
patent: 1 233 070 (2002-08-01), None
patent: 1233068 (2002-08-01), None
patent: 1233069 (2002-08-01), None
patent: 1 233 068 (2002-11-01), None
patent: 1352966 (2003-10-01), None
patent: 36-017712 (1961-09-01), None
patent: 38-016459 (1963-08-01), None
patent: 45-011286 (1970-04-01), None
patent: 61-139398 (1986-06-01), None
patent: 61-268185 (1986-11-01), None
patent: 62-000288 (1987-01-01), None
patent: 63-214189 (1988-09-01), None
patent: 10-059911 (1998-03-01), None
patent: WO97/08294 (1997-03-01), None
Hiramatsu S. Sudies on the polymorphic crystalization of L-glutamic acid in the presence of co-existant substances. Part II. Effects of amino acids and therir derivatives, peptides and proteins on the apha to beta polymorphic transition of L-glutamic acid crystal, Nippon Nogie Kagaku Kaishi (19977), 51(1), 38-46; abstract.
Kitamura M. et al., In situ Observation of Growth Process of alpha-L-Glutamic Acid with Atomic Force Microscopy, Journal of Colloid and Interface Science, 2000, 224, 311-316.
International Search Report for PCT App. No. PCT/JP2004/006031 (Jun. 22, 2004).
Bernal, J. D., “Kürzere Originalmitteilunge und Notizen. The Crystal Structure of the Natural Amino Acids and Related Compounds,” Z. Krist. 1931;78:363-369.
Hirokawa, S., “A New Modification of L-Glutamic Acid and its Crystal Structure,” Acta Cryst. 1955;8:637-641.
Takahashi, H., et al., “Quantitative Analysis of Mixtures of L-Glutamic Acid Polymorphs by X-Ray Diffraction,” Bull. Chem. Soc. Japan 1962;35:923-926.
International Preliminary Report on Patentability for PCT Appl. No. PCT/JP2004/006031 (Mar. 23, 2006).
Bailey, J. E., “Toward a Science of Metabolic Engineering,” Science 1991;252:1668-1675.
Borichewski, R. M., “Keto Acids as Growth-limiting Factors in Autotrophic Growth ofThiobacillus thiooxidans,” J. Bacteriol. 1967;93(2):597-599.
Chao, K.-C., et al., “A Glutamic Acid-Producing Bacillus,” J. Bacteriol 1959;77(6):715-725.
Jetten, M.S., et al., “Recent advances in the physiologu and genetics of amino acod-producing bacteria,” Crit. Rev. Biotechnol. 1995;15(1):73-103 (abstract).
Kwon, S.-W., et al., “Phylogenetic Analysis ofErwiniaSpecies Based on 16S rRNA Gene Sequences,” Int. J. Sys. Bacteriol. 1997;47(4):1061-1067.
Mergaert, J., et al., “Transfer ofErwinia ananas(synonym,Erwinia uredovora) andErwinia stewartiito the GenusPantoeaemend. asPantoea ananas(Serrano 1928) comb. nov. andPantoea stewartii(Smith 1898) comb. nov., Respectively, and Description ofPantoea stewartiisubsp.indologenessubsp. nov.” Int. J. Sys. Bacteriol. 1993;43(1):162-173.
WPI/Derwent Abstract, “Manufacturing L-glutamic acid by fermentation for foodstuff, pharmaceutical—comprises culturingCorynebacterium striatamin culture medium,” JP-11009296 (1999) (abstract).
U.S. Appl. No. 09/419,611, filed Oct. 18, 1999, inventor Izui et al., now US Patent 7,247,459.
Toumori Kunihiko
Ueda Hiroshi
Ajinomoto Co. Inc.
Cermak Shelly Guest
Cermak Kenealy & Vaidya LLP
Prouty Rebecca E.
Walicka Malgorzata A.
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