Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2007-02-13
2007-02-13
McKenzie, Thomas (Department: 1625)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C546S137000
Reexamination Certificate
active
11031623
ABSTRACT:
The subject invention provides stereoisomeric compounds of formula (X):wherein the variables are as defined herein, and compositions for the safe and effective treatment of various gastrointestinal disorders including, but not limited to, gastroparesis, gastroesophageal reflux and related conditions. The compounds of the subject invention are also useful in treating a variety of conditions involving the central nervous system.
REFERENCES:
patent: 3536809 (1970-10-01), Applezweig
patent: 3598123 (1971-08-01), Zaffaroni
patent: 3845770 (1974-11-01), Theeuwes et al.
patent: 3916899 (1975-11-01), Theeuwes et al.
patent: 4008719 (1977-02-01), Theeuwes et al.
patent: 4870074 (1989-09-01), Kon et al.
patent: 4962115 (1990-10-01), Van Daele
patent: 4975439 (1990-12-01), Van Daele et al.
patent: 5041454 (1991-08-01), Van Daele et al.
patent: 5057525 (1991-10-01), Van Daele
patent: 5137896 (1992-08-01), Van Daele
patent: 5395832 (1995-03-01), Ito et al.
patent: 5423872 (1995-06-01), Cigaina
patent: 5500422 (1996-03-01), Ito et al.
patent: 5618828 (1997-04-01), Gray et al.
patent: 5629328 (1997-05-01), Gray et al.
patent: 5629329 (1997-05-01), Gray et al.
patent: 5705498 (1998-01-01), Gaster et al.
patent: 5712293 (1998-01-01), McCullough et al.
patent: 5739151 (1998-04-01), McCullough et al.
patent: 5877188 (1999-03-01), McCullough et al.
patent: 5877189 (1999-03-01), McCullough et al.
patent: 5955477 (1999-09-01), Gray et al.
patent: 5955478 (1999-09-01), Gray et al.
patent: 6066654 (2000-05-01), Gray et al.
patent: 6114356 (2000-09-01), McCullough et al.
patent: 6147093 (2000-11-01), McCullough et al.
patent: 6242465 (2001-06-01), McCullough et al.
patent: 6331401 (2001-12-01), Gerald et al.
patent: 6552046 (2003-04-01), Druzgala et al.
patent: 6632827 (2003-10-01), McCullough et al.
patent: 6638951 (2003-10-01), Kato et al.
patent: 2003/0216387 (2003-11-01), Druzgala et al.
patent: 2004/0092511 (2004-05-01), Billstein et al.
patent: 19933926 (2001-01-01), None
patent: 0076530 (1983-04-01), None
patent: 0309043 (1989-03-01), None
patent: 0640601 (1994-03-01), None
patent: 1149832 (2001-10-01), None
patent: 1425706 (1976-02-01), None
patent: 11292846 (1999-10-01), None
patent: WO-99/02496 (1999-01-01), None
patent: WO-01/093849-A3 (2001-12-01), None
Paakkari et al., Toxicology Letters, “Cardiotoxicity of new antihistamines and cisapride”,2002, vol. 127, pp. 279-284.
Barnes, N.M., et al. (Apr. 5, 1998) “Identification of 5-HT .sub.3 recognition sites in the ferret area postrema”, J. Pharm. Pharmacol. 40:586-588.
Decktor, Dennis, et al. (1988) “Effect of metoclopramide, bethanechol and the cholecystokinin receptor antagonist, L-364,718, on gastric emptying in the rat”, European Journal of Pharmacology 147:313-316.
Stacher, Georg, et al. (Nov. 1987) “Effects of Oral Cisapride on Interdigestive jejunal Motor Activity, Psychomotor Function, and Side-Effect Profile in Healthy Man”, Digestive Diseases and Sciences 32(11):1223-1230.
Van Daele, Georges H.P., et al. (1986) “Synthesis of Cisapride, a Gastrointestinal Stimulant Derived From Cis-4-Amino-3-Methoxypiperidine”, Drug Development Research 8:225-232.
Sanger et al., “Preparation of substituted indol-3-yl . . . ” CA 119:72611 (1993).
Dean et al., “No change in the density of serotonin 1a . . . ” CA 131:30595 (1999).
Sakurai et al., “Involvement of the 5-hydroxytriptamine 4 . . . ” CA 139:115744 (2003).
Stoinov et al., “Evaluation of the effects of the medications . . . ” CA 135:251747 (2001).
Ohuchi et al., “Preparation of quinolinecarboxylic . . . ” CA 124:202043 (1996).
Becker Cyrus
Irwin Ian
Palme Monica
ARYx Therapeutics
McDonnell Boehnen & Hulbert & Berghoff LLP
McKenzie Thomas
Rahmani Niloofar
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