Difluoro antivirals and intermediate therefor

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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536 23, 536 24, 536 26, 536 11, C07D30732

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active

045269882

ABSTRACT:
A 2,2-difluoro-2-desoxycarbohydrate is used to prepare antiviral nucleosides.

REFERENCES:
patent: 2359096 (1944-09-01), Elderfield
patent: 2359208 (1944-09-01), Elderfield
patent: 4211773 (1980-07-01), Lopez et al.
patent: 4352795 (1982-10-01), Cook
DeClercq et al., Proc. Natl. Acad. Sci. USA 76, 2947-2951 (1979).
J. Med. Chem. 22, 21-24 (1979).
Howard J. Schaeffer, American Journal of Medicine, Jul. 1982, 4-6.
Kaufman and Heidelberger, Science 145, 585-586 (1964).
Prusoff, Biochim. Biophys. Acta 32, 295-296 (1959).
Witkowski et al., J. Med. Chem. 15, 1150-1154 (1972).
De Rudder and De Garilhe, Antimicrobial Agents and Chemotherapy, 578-584 (1965).
Penglis, Advances in Carbohydrate Chemistry and Biochemistry 38, 195-285 (1981).
Fox et al., Seventh International Symposium of Medicinal Chemistry, 1980, published by Pergamon Press (1981), pp. 27-39.
Reichman et al., Carbohydrate Research 42, 233-249 (1975).
Wright and Taylor, Carbohydrate Research 6, 347-354 (1968).
Adamson et al., Carbohydrate Research 18, 345-347 (1971).
Hough et al., J. Chem. Soc. Perkin I, 784-788 (1972).
Masamune, Sharpless et al., J. Org. Chem. 47, 1373-1381 (1982).
Abstract, Spring 1983 ACS Meeting at Seattle, D. E. Bergstrom.

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