Process for the synthesis of perindopril and...

Details Process for the synthesis of perindopril and... Process for the synthesis of perindopril and...

2007-10-09

2007-10-09

Saeed, Kamal A. (Department: 1626)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

active

10582283

ABSTRACT:
Process for the industrial synthesis of perindopril of formula (I):and pharmaceutically acceptable salts thereof.

REFERENCES:
patent: 01/58868 (2001-08-01), None
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Li, Peng, et al., “The development of highly efficient anium-type peptide coupling reagents based upon rational molecular design” Journal of Peptide Research, vol. 58, No. 2, p. 129-139, 2001.
Coste, Jacques, et al. “Oxybenzotriazole free peptide coupling reagents for N-methylate amino acids” Tetrahedron Letters, vol. 32, No. 17, p. 1967-1970, 1991.
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Chen, Shaoqing, et al, “A coupling reagent for peptide synthesis. Benzotriazolyloxybis(pyrrolidine)carbonium hexafluorophosphate(BBC)” Tetrahedron Letters, vol. 33, No. 5, p. 647-650, 1992.
International Search Report for PCT/FR2004/003166—May 3, 2005.
European Search Report for EP 03293084—Mar. 18, 2004.

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