Process for the preparation of thioalkylamine derivatives

Details Process for the preparation of thioalkylamine derivatives Process for the preparation of thioalkylamine derivatives

2007-06-26

2007-06-26

Powers, Fiona T. (Department: 1626)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C548S174000, C564S341000, C564S500000, C564S501000

Reexamination Certificate

active

10515441

ABSTRACT:
The present invention relates to a novel process for the preparation of compounds of the formula (I)by reacting in a first step amino alcohols of the formula (II)with oleum to give sulphuric acid esters of the general formula (III)and by reacting these sulphuric acid esters in a second step with mercaptans or salts thereof of the general formula (IV)in-line-formulae description="In-line Formulae" end="lead"?RSM   (IV)in-line-formulae description="In-line Formulae" end="tail"?wherein in each formula, where applicable, R1, R2, R3, R4, R5, R6, R, n and M have the meanings given in the disclosure,in the presence of a diluent and in the presence of a base.

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