Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Reexamination Certificate
2007-02-20
2007-02-20
O'Hara, Eileen (Department: 1647)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
C536S023100, C536S023200, C536S024300, C536S024310, C536S024330, C530S351000
Reexamination Certificate
active
10727021
ABSTRACT:
DNAs encoding the human histamine H3 receptor have been cloned and characterized. The recombinant protein is capable of forming biologically active histamine H3 receptor protein. The cDNA's have been expressed in recombinant host cells which produce active recombinant protein. The recombinant protein is also purified from the recombinant host cells. In addition, the recombinant host cells are utilized to establish a method for identifying modulators of the receptor activity, and receptor modulators are identified.
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Erlander Mark
Huvar Arne
Lovenberg Timothy W.
Pyati Jayashree
Hamud Fozia
O'Hara Eileen
Ortho-McNeil Pharmaceutical , Inc.
Woodcock & Washburn LLP
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