Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Reexamination Certificate
2007-01-09
2007-01-09
Allen, Marianne P. (Department: 1647)
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
C435S325000, C435S320100, C536S023100
Reexamination Certificate
active
10413600
ABSTRACT:
A nucleic acid sequence encoding a polypeptide having antibacterial activity, which nucleic acid sequence has the nucleotide sequence of Bases 198 to 452 of Seq. ID No. 13 or is a nucleic acid that hybridizes under highly stringent conditions to a complement of a nucleic acid having the nucleotide sequence of Bases 198 to 452 of Seq. ID No. 13, and the polypeptide encoded thereby.
REFERENCES:
patent: 6011012 (2000-01-01), Ni et al.
patent: WO 98/08534 (1998-03-01), None
Lewis et al. Subracted Lewin Cattle Spleen ESTs. Accession Number: BM366436. See Appendix A (Jan. 19, 2002).
Meinkoth et al. Hybridization of of Nucleic Acids Immobilized on Solid Supports. Analytical Biochemistry vol. 138:267-284, (1984).
Wyckoff III, JH, et al., Comparison ofBrucella abortusantigen preparations for in vitro stimulation of immune bovine T-lymphocyte cell lines,Veterinary Immunology and Immunopathology, vol. 36, pp. 45-64 (1993).
Andersson, M., et al., NK-lysin, a novel effector peptide of cytotoxic T and NK cells. Structure and cDNA cloning of the porcine form, induction by interleukin 2, antibacterial and antitumor activity,EMBO Journal, vol. 14, No. 8, pp. 1615-1625 (1995).
Andersson, M., et al., NK-lysin, structure and function of a novel effector molecule of porcine T and NK cells,Veterinary Immunology and Immunopathology, vol. 54, pp. 123-126 (1996).
Pena, SV., et al., Processing, subcellular localization, and function of 519 (Granulysin), a human late T cell activation molecule with homology to small, lytic granule proteins,American Association of Immunologists, vol. 158, pp. 2680-2688 (1997).
Garcia-Penarrubia, P. et al., Prostaglandins from human T suppressor/cytotoxic cells modulate natural killer antibacterial activity,Journal of Experimental Medicine, vol. 170, pp. 601-606 (1989).
Garcia-Penarrubia, P., et al., Antibacterial activity of human natural killer cells,Journal of Experimental Medicine, vol. 169, pp. 99-113 (1989).
Levitz, SM, et al., Direct antimicrobial activity of T cells,Immunology Today, vol. 16, pp. 387-391 (1995).
Quiroga, GH, et al., Cytologic responses ofStaphylococcus aureus-infected mammary glands of heifers to interferon gamma and interleukin-2 treatment,American Journal of Veterinary Research, vol. 54, No. 11, pp. 1894-1900 (1993).
Louhi-Lehtio, M., et al, Antibacterial Susceptibility of Bovine-mastitis Pathogens tested directely in milk from infected quarters,J. Vet. Med. I, 41:101-112 (1994).
Singh, PK, et al., Synergistic and additive killing by antimicrobial factors found in human airway surface liquid,Am. J. Physiol. Lung Cell Mol. Physiol., 279:L799-L805 (2000).
Sable, S., Antibacterial Activity evaluation of Microcin J25 against diarrheagenicEscherichia coli, Applied and Environmental Microbiology, 66(10):4595-4597 (2000).
Pettit, DK and Gombotz, WR, The development of site-specific drug-delivery systems for protein and peptide biopharmaceuticals,Tibtechl, 16:343-349 (1998).
Gaddy, J., and Broxmeyer, HE, Cord Blood CD16+45- cells with low lytic activity are possible precursors of mature natural killer cells,Cellular Immunology, 180:132-142 (1997).
Lotzova, E. and Savary, CA, Human natural killer cell development from bone marrow progenitors: analysis of phenotype, cytotoxicity and growth,Nat. Immun., 12:209-217 (1993).
Allen Marianne P.
DeBerry Regina M.
Eisenberg, Esq. Howard
The Penn State Research Foundation
LandOfFree
Bovine lymphocyte-derived antibacterial protein does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Bovine lymphocyte-derived antibacterial protein, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Bovine lymphocyte-derived antibacterial protein will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3814542